Pseudomonas aeruginosa PAO1, PA5410 (gbcA)

Annotation Updates

Date	Description	Acknowledgements
Jan 10, 2008	New alternate product name: glycine betaine catabolism protein. New gene name: gbcA (Existing value: blank). New product name: GbcA (Existing value: probable ring hydroxylating dioxygenase, alpha-subunit). New product name confidence: Class 1 (Existing value: Class 3). New PseudoCAP function class: Amino acid biosynthesis and metabolism. New evidence reference (PMID): 17951379. New pathway: glycine betaine catabolism. New comment: Strains with deletions in gbcA are unable to grow on choline or glycine betaine but are able to grow on dimethylglycine. NMR analysis shows buildup of labeled glycine betaine when gbcA mutants are given labeled choline.	Matthew Wargo and Deborah Hogan, Dartmouth Medical School, USA