Pseudomonas aeruginosa PAO1, PA5411 (gbcB)

Gene Ontology

Ontology	Accession	Term	GO Evidence	Evidence Ontology (ECO) Code	Reference	Comments
Biological Process	GO:0031457	glycine betaine catabolic process	IMP Inferred from Mutant Phenotype	ECO:0000015 mutant phenotype evidence	17951379	Reviewed by curator
Molecular Function	GO:0016491	oxidoreductase activity	IDA Inferred from Direct Assay	ECO:0000314 direct assay evidence used in manual assertion	17951379	Reviewed by curator
Molecular Function	GO:0016491	oxidoreductase activity	ISM Inferred from Sequence Model Term mapped from: InterPro:PF00175	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0051536	iron-sulfur cluster binding	ISM Inferred from Sequence Model Term mapped from: InterPro:PF00111	ECO:0000259 match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Amino acid biosynthesis and metabolism Other PAO1 genes in this class

Pathways

Database	Xref	Pathway	Version	Evidence	PMID
PseudoCAP		glycine betaine catabolism		ECO:0000037 not_recorded

Functional Predictions from Interpro

Analysis	Accession	Description	Interpro Accession	Interpro Description	Amino Acid Start	Amino Acid Stop	E-value
CDD	cd06215	FNR_iron_sulfur_binding_1	-	-	21	252	0.0
Pfam	PF00111	2Fe-2S iron-sulfur cluster binding domain	IPR001041	2Fe-2S ferredoxin-type iron-sulfur binding domain	290	359	1.6E-12
FunFam	G3DSA:3.10.20.30:FF:000041	Glycine-betaine demethylase subunit GbcB	-	-	263	366	1.1E-68
PRINTS	PR00406	Cytochrome B5 reductase signature	-	-	164	175	4.4E-9
Gene3D	G3DSA:3.10.20.30	-	IPR012675	Beta-grasp domain superfamily	263	366	9.5E-25
PRINTS	PR00371	Flavoprotein pyridine nucleotide cytochrome reductase signature	IPR001709	Flavoprotein pyridine nucleotide cytochrome reductase	67	74	2.0E-5
Pfam	PF00175	Oxidoreductase NAD-binding domain	IPR001433	Oxidoreductase FAD/NAD(P)-binding	128	234	2.6E-14
FunFam	G3DSA:3.40.50.80:FF:000056	Probable ferredoxin	-	-	120	259	5.9E-100
Gene3D	G3DSA:2.40.30.10	Translation factors	-	-	13	114	2.0E-25
PRINTS	PR00406	Cytochrome B5 reductase signature	-	-	220	228	4.4E-9
PRINTS	PR00406	Cytochrome B5 reductase signature	-	-	67	74	4.4E-9
Gene3D	G3DSA:3.40.50.80	-	IPR039261	Ferredoxin-NADP reductase (FNR), nucleotide-binding domain	120	259	1.3E-30
Pfam	PF00970	Oxidoreductase FAD-binding domain	IPR008333	Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain	25	116	5.6E-16
SUPERFAMILY	SSF54292	2Fe-2S ferredoxin-like	IPR036010	2Fe-2S ferredoxin-like superfamily	243	365	7.6E-29
PRINTS	PR00371	Flavoprotein pyridine nucleotide cytochrome reductase signature	IPR001709	Flavoprotein pyridine nucleotide cytochrome reductase	127	146	2.0E-5
SUPERFAMILY	SSF63380	Riboflavin synthase domain-like	IPR017938	Riboflavin synthase-like beta-barrel	13	117	1.86E-29
PRINTS	PR00406	Cytochrome B5 reductase signature	-	-	104	118	4.4E-9
SUPERFAMILY	SSF52343	Ferredoxin reductase-like, C-terminal NADP-linked domain	IPR039261	Ferredoxin-NADP reductase (FNR), nucleotide-binding domain	108	250	3.67E-37
PRINTS	PR00371	Flavoprotein pyridine nucleotide cytochrome reductase signature	IPR001709	Flavoprotein pyridine nucleotide cytochrome reductase	220	228	2.0E-5
PRINTS	PR00371	Flavoprotein pyridine nucleotide cytochrome reductase signature	IPR001709	Flavoprotein pyridine nucleotide cytochrome reductase	164	175	2.0E-5
CDD	cd00207	fer2	IPR001041	2Fe-2S ferredoxin-type iron-sulfur binding domain	289	365	2.05134E-21
PANTHER	PTHR47354	NADH OXIDOREDUCTASE HCR	-	-	17	365	1.3E-105
PRINTS	PR00406	Cytochrome B5 reductase signature	-	-	127	146	4.4E-9

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.