Pseudomonas aeruginosa PAO1, PA5418 (soxA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0008115 sarcosine oxidase activity
IMP
Inferred from Mutant Phenotype
ECO:0000315
mutant phenotype evidence used in manual assertion
17951384 Reviewed by curator
Biological Process GO:1901053 sarcosine catabolic process
IMP
Inferred from Mutant Phenotype
ECO:0000015
mutant phenotype evidence
17951379 Reviewed by curator
Biological Process GO:1901053 sarcosine catabolic process
IMP
Inferred from Mutant Phenotype
ECO:0000315
mutant phenotype evidence used in manual assertion
17951383 Reviewed by curator
Biological Process GO:0055114 oxidation-reduction process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00469
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0005515 protein binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:3.30.1360.120
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0046653 tetrahydrofolate metabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF037980
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016491 oxidoreductase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00469
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0008115 sarcosine oxidase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF037980
ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Carbon compound catabolism Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG (InterPro) 00670 One carbon pool by folate InterPro 5.8-49.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG pae01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG (InterPro) 00260 Glycine, serine and threonine metabolism InterPro 5.8-49.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG pae00260 Glycine, serine and threonine metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCyc CRNFORCAT-PWY creatinine degradation I 19.5 ECO:0000250
sequence similarity evidence used in manual assertion
12867747
PseudoCAP glycine betaine catabolism ECO:0000037
not_recorded

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Gene3D G3DSA:3.30.1360.120 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 762 873 2.2E-87
Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 17 102 6.3E-23
Gene3D G3DSA:3.10.20.440 12 108 9.9E-7
Gene3D G3DSA:3.30.70.1400 874 895 2.2E-87
Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase IPR023753 FAD/NAD(P)-binding domain 172 434 2.2E-12
Gene3D G3DSA:2.40.30.110 909 1003 2.7E-7
Gene3D G3DSA:3.50.50.60 IPR036188 FAD/NAD(P)-binding domain superfamily 588 592 6.2E-85
PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II 172 194 2.8E-10
PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II 284 292 2.8E-10
Pfam PF01571 Aminomethyltransferase folate-binding domain IPR006222 Aminomethyltransferase, folate-binding domain 619 884 2.6E-75
SUPERFAMILY SSF51905 IPR036188 FAD/NAD(P)-binding domain superfamily 167 448 1.1E-33
PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 283 301 4.5E-8
Gene3D G3DSA:3.50.50.60 IPR036188 FAD/NAD(P)-binding domain superfamily 423 507 6.2E-85
Gene3D G3DSA:3.30.1360.120 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 614 671 2.2E-87
Gene3D G3DSA:3.30.70.1400 672 761 2.2E-87
Gene3D G3DSA:3.50.50.60 IPR036188 FAD/NAD(P)-binding domain superfamily 385 422 6.2E-85
Gene3D G3DSA:3.50.50.60 IPR036188 FAD/NAD(P)-binding domain superfamily 295 359 6.2E-85
Gene3D G3DSA:1.10.10.1100 508 587 6.2E-85
SUPERFAMILY SSF103025 613 895 1.4E-92
TIGRFAM TIGR01372 soxA: sarcosine oxidase, alpha subunit family IPR006277 Sarcosine oxidase, alpha subunit 2 1004 0.0
SUPERFAMILY SSF101790 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal 906 1003 1.16E-17
PIRSF PIRSF037980 IPR006277 Sarcosine oxidase, alpha subunit 1 1004 0.0
Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain IPR013977 Glycine cleavage T-protein, C-terminal barrel domain 907 990 4.5E-11
PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 173 192 4.5E-8
Gene3D G3DSA:3.50.50.60 IPR036188 FAD/NAD(P)-binding domain superfamily 172 294 6.2E-85
PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II 459 477 2.8E-10

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.