Pseudomonas aeruginosa PAO1, PA5420 (purU2)

Gene Ontology

Ontology	Accession	Term	GO Evidence	Evidence Ontology (ECO) Code	Reference	Comments
Molecular Function	GO:0008864	formyltetrahydrofolate deformylase activity	ISS Inferred from Sequence or Structural Similarity	ECO:0000250 sequence similarity evidence used in manual assertion	7868604	Reviewed by curator
Biological Process	GO:0009152	purine ribonucleotide biosynthetic process	ISS Inferred from Sequence or Structural Similarity	ECO:0000250 sequence similarity evidence used in manual assertion	7868604	Reviewed by curator
Biological Process	GO:0006189	'de novo' IMP biosynthetic process	ISM Inferred from Sequence Model Term mapped from: InterPro:PR01575	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0008864	formyltetrahydrofolate deformylase activity	ISM Inferred from Sequence Model Term mapped from: InterPro:cd08648	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Biological Process	GO:0009058	biosynthetic process	ISM Inferred from Sequence Model Term mapped from: InterPro:SSF53328	ECO:0000259 match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Nucleotide biosynthesis and metabolism Other PAO1 genes in this class

Pathways

Database	Xref	Pathway	Version	Evidence	PMID
KEGG	pae00670	One carbon pool by folate	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
KEGG	pae00630	Glyoxylate and dicarboxylate metabolism	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
PseudoCAP		Glyoxylate and dicarboxylate metabolism		ECO:0000037 not_recorded
PseudoCAP		One carbon pool by folate		ECO:0000037 not_recorded

Functional Predictions from Interpro

Analysis	Accession	Description	Interpro Accession	Interpro Description	Amino Acid Start	Amino Acid Stop	E-value
CDD	cd04875	ACT_F4HF-DF	IPR044074	Formyltetrahydrofolate deformylase, ACT domain	9	79	3.26934E-21
SUPERFAMILY	SSF53328	Formyltransferase	IPR036477	Formyl transferase, N-terminal domain superfamily	92	284	3.53E-59
PANTHER	PTHR42706	FORMYLTETRAHYDROFOLATE DEFORMYLASE	IPR004810	Formyltetrahydrofolate deformylase	5	285	8.0E-81
PRINTS	PR01575	Formyltetrahydrofolate deformylase signature	IPR004810	Formyltetrahydrofolate deformylase	259	284	1.6E-43
Gene3D	G3DSA:3.40.50.170	-	-	-	90	285	1.2E-56
Hamap	MF_01927	Formyltetrahydrofolate deformylase [purU].	IPR004810	Formyltetrahydrofolate deformylase	5	285	42.906277
PRINTS	PR01575	Formyltetrahydrofolate deformylase signature	IPR004810	Formyltetrahydrofolate deformylase	113	140	1.6E-43
Gene3D	G3DSA:3.30.70.260	-	-	-	1	87	6.2E-20
Pfam	PF00551	Formyl transferase	IPR002376	Formyl transferase, N-terminal	91	266	6.8E-36
PRINTS	PR01575	Formyltetrahydrofolate deformylase signature	IPR004810	Formyltetrahydrofolate deformylase	237	259	1.6E-43
PRINTS	PR01575	Formyltetrahydrofolate deformylase signature	IPR004810	Formyltetrahydrofolate deformylase	91	113	1.6E-43
PIRSF	PIRSF036480	FormyFH4_hydr	-	-	5	285	9.6E-97
PRINTS	PR01575	Formyltetrahydrofolate deformylase signature	IPR004810	Formyltetrahydrofolate deformylase	10	36	1.6E-43
PRINTS	PR01575	Formyltetrahydrofolate deformylase signature	IPR004810	Formyltetrahydrofolate deformylase	42	54	1.6E-43
CDD	cd08648	FMT_core_Formyl-FH4-Hydrolase_C	IPR041729	Formyltetrahydrofolate deformylase, C-terminal hydrolase domain	92	285	8.08019E-124

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.