Pseudomonas aeruginosa PAO1, PA5478

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA5478
Name
Replicon chromosome
Genomic location 6168842 - 6170071 (- strand)
Transposon Mutants 7 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_254165.1
GI 15600671
Affymetrix PA5478_at
Entrez 877683
GenBank AAG08863.1
INSDC AAG08863.1
NCBI Locus Tag PA5478
protein_id(GenBank) gb|AAG08863.1|AE004960_6|gnl|PseudoCAP|PA5478
TIGR NTL03PA05479
UniParc UPI00000C602B
UniProtKB Acc Q9HT92
UniProtKB ID Q9HT92_PSEAE
UniRef100 UniRef100_W0Z2Q9
UniRef50 UniRef50_Q88B96
UniRef90 UniRef90_A6VEV2

Product

Feature Type CDS
Coding Frame 1
Product Name
conserved hypothetical protein
Product Name Confidence: Class 4
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 1.62
Kyte-Doolittle Hydrophobicity Value 0.949
Molecular Weight (kDa) 43.0
Isoelectric Point (pI) 8.05

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 126 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG005019 (536 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA5478

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295