Pseudomonas aeruginosa PAO1, PA5538 (amiA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Cellular Component GO:0009276 Gram-negative-bacterium-type cell wall
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000044
sequence similarity evidence
Biological Process GO:0009253 peptidoglycan catabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00646
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0008745 N-acetylmuramoyl-L-alanine amidase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00646
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Cell wall / LPS / capsule Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pae01503 Cationic antimicrobial peptide (CAMP) resistance 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
PANTHER PTHR30404 N-ACETYLMURAMOYL-L-ALANINE AMIDASE - - 1 380 4.9E-89
SUPERFAMILY SSF53187 Zn-dependent exopeptidases - - 155 379 1.35E-51
Gene3D G3DSA:2.60.40.3500 - - - 17 132 6.6E-27
Pfam PF11741 AMIN domain IPR021731 AMIN domain 32 129 4.5E-17
FunFam G3DSA:3.40.630.40:FF:000001 N-acetylmuramoyl-L-alanine amidase - - 146 382 1.6E-101
Pfam PF01520 N-acetylmuramoyl-L-alanine amidase IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain 157 375 3.0E-44
Gene3D G3DSA:3.40.630.40 - - - 149 382 1.7E-66
CDD cd02696 MurNAc-LAA IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain 157 375 1.42838E-62
SMART SM00646 ami_3 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain 217 375 1.3E-66

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.