Pseudomonas aeruginosa PAO1, PA5552 (glmU)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0003977 UDP-N-acetylglucosamine diphosphorylase activity
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000250
sequence similarity evidence used in manual assertion		 8555230 Reviewed by curator
Biological Process GO:0006048 UDP-N-acetylglucosamine biosynthetic process
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000250
sequence similarity evidence used in manual assertion		 8407787 Reviewed by curator
Molecular Function GO:0019134 glucosamine-1-phosphate N-acetyltransferase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01173
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0000902 cell morphogenesis
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01173
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003977 UDP-N-acetylglucosamine diphosphorylase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01173
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Cellular Component GO:0005737 cytoplasm
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01173
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0009252 peptidoglycan biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01173
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006048 UDP-N-acetylglucosamine biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01173
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0000287 magnesium ion binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01173
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Cell wall / LPS / capsule Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pae00520 Amino sugar and nucleotide sugar metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCyc OANTIGEN-PWY O-antigen building blocks biosynthesis (E. coli) 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747
KEGG pae01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae01130 Biosynthesis of antibiotics 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCAP Aminosugars metabolism ECO:0000037
not_recorded
PseudoCyc KDO-PEP-LIPASYN-PWY KDO<SUB>2</SUB>-lipid A and peptidoglycan biosynthesis 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747
PseudoCyc PEP-LIPA-SYN-PWY peptidoglycan and lipid A precursor biosynthesis 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747
PseudoCyc UDPNAGSYN-PWY UDP-N-acetyl-D-glucosamine biosynthesis I 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Pfam PF14602 Hexapeptide repeat of succinyl-transferase IPR001451 Hexapeptide repeat 394 425 2.7E-5
Gene3D G3DSA:3.90.550.10 Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A IPR029044 Nucleotide-diphospho-sugar transferases 1 224 5.2E-71
CDD cd03353 LbH_GlmU_C IPR038009 GlmU, C-terminal LbH domain 248 440 1.29457E-121
PANTHER PTHR43584 NUCLEOTIDYL TRANSFERASE - - 1 420 0.0
Pfam PF12804 MobA-like NTP transferase domain IPR025877 MobA-like NTP transferase 6 121 1.8E-24
Hamap MF_01631 Bifunctional protein GlmU [glmU]. IPR005882 Bifunctional protein GlmU 2 449 43.32618
CDD cd02540 GT2_GlmU_N_bac - - 5 228 1.82084E-124
SUPERFAMILY SSF51161 Trimeric LpxA-like enzymes IPR011004 Trimeric LpxA-like superfamily 252 439 2.45E-49
SUPERFAMILY SSF53448 Nucleotide-diphospho-sugar transferases IPR029044 Nucleotide-diphospho-sugar transferases 1 249 1.07E-63
NCBIfam TIGR01173 JCVI: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase IPR005882 Bifunctional protein GlmU 4 451 0.0
Pfam PF00132 Bacterial transferase hexapeptide (six repeats) IPR001451 Hexapeptide repeat 264 296 1.3E-7
Gene3D G3DSA:2.160.10.10 Hexapeptide repeat proteins - - 225 453 1.5E-72

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.