Pseudomonas aeruginosa UCBPP-PA14, PA14_02110

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_02110
Name
Replicon chromosome
Genomic location 191825 - 192532 (- strand)
Transposon Mutants 1 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 18 transposon mutants in orthologs

Cross-References

RefSeq YP_788327.1
GI 116053890
Entrez 4383569
INSDC ABJ15126.1
NCBI Locus Tag PA14_02110
UniParc UPI00000C4F78
UniProtKB Acc Q02UQ9
UniProtKB ID Q02UQ9_PSEAB
UniRef100 UniRef100_Q9I6W3
UniRef50 UniRef50_Q9I6W3
UniRef90 UniRef90_Q9I6W3

Product

Feature Type CDS
Coding Frame 1
Product Name
diguanylate cyclase
Synonyms
Evidence for Translation
Charge (pH 7) 4.91
Kyte-Doolittle Hydrophobicity Value -0.539
Molecular Weight (kDa) 26.8
Isoelectric Point (pI) 9.49

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
7E6G DE NOVO PROTEIN 02/22/21 Crystal structure of diguanylate cyclase SiaD in complex with its activator SiaC from Pseudomonas aeruginosa Pseudomonas aeruginosa 2.65 X-RAY DIFFRACTION 95.7

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 454 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000167 (2758 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_02110

Human Homologs

References

No references are associated with this feature.