Pseudomonas aeruginosa UCBPP-PA14, PA14_04110 (serA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0051287 NAD binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF02826
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00389
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Amino acid biosynthesis and metabolism Other UCBPP-PA14 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pau00260 Glycine, serine and threonine metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau01230 Biosynthesis of amino acids 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau00680 Methane metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau01120 Microbial metabolism in diverse environments 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau01130 Biosynthesis of antibiotics 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau01200 Carbon metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
SUPERFAMILY SSF52283 Formate/glycerate dehydrogenase catalytic domain-like - - 7 136 3.4E-51
FunFam G3DSA:3.30.70.260:FF:000007 D-3-phosphoglycerate dehydrogenase - - 328 408 2.1E-39
FunFam G3DSA:3.40.50.720:FF:000041 D-3-phosphoglycerate dehydrogenase - - 109 297 8.5E-78
SUPERFAMILY SSF55021 ACT-like IPR045865 ACT-like domain 334 408 2.75E-16
PANTHER PTHR43761 D-ISOMER SPECIFIC 2-HYDROXYACID DEHYDROGENASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_1G13630) - - 10 318 2.9E-67
Gene3D G3DSA:3.30.70.260 - - - 328 408 4.8E-33
SUPERFAMILY SSF51735 NAD(P)-binding Rossmann-fold domains IPR036291 NAD(P)-binding domain superfamily 108 295 3.26E-52
Gene3D G3DSA:3.40.50.720 - - - 109 297 4.9E-111
Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain 119 294 8.3E-47
Gene3D G3DSA:3.40.50.720 - - - 14 313 4.9E-111
Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 14 326 3.9E-38
CDD cd04901 ACT_3PGDH - - 340 408 3.45778E-27
CDD cd12176 PGDH_3 - - 11 315 0.0

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.