Pseudomonas aeruginosa UCBPP-PA14, PA14_04670 (mutM)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0006281 DNA repair
ISS
Inferred from Sequence or Structural Similarity
Term mapped from: PseudoCAP:PA0357
 ECO:0000249
sequence similarity evidence used in automatic assertion		 12445642
Molecular Function GO:0016787 hydrolase activity
ISS
Inferred from Sequence or Structural Similarity
Term mapped from: PseudoCAP:PA0357
 ECO:0000249
sequence similarity evidence used in automatic assertion		 12445642
Molecular Function GO:0003676 nucleic acid binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF46946
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0008270 zinc ion binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM01232
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0019104 DNA N-glycosylase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00898
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006281 DNA repair
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00103
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM01232
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM01232
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006284 base-excision repair
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM01232
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0008534 oxidized purine nucleobase lesion DNA N-glycosylase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00103
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003684 damaged DNA binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM01232
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

DNA replication, recombination, modification and repair Other UCBPP-PA14 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pau03410 Base excision repair 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
SUPERFAMILY SSF46946 S13-like H2TH domain IPR010979 Small ribosomal subunit protein uS13-like, H2TH 131 222 1.09E-27
SUPERFAMILY SSF81624 N-terminal domain of MutM-like DNA repair proteins IPR035937 MutM-like, N-terminal 2 135 1.15E-40
FunFam G3DSA:3.20.190.10:FF:000001 Formamidopyrimidine-DNA glycosylase - - 2 129 3.4E-48
SMART SM01232 H2TH_2 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding 130 222 6.8E-46
Gene3D G3DSA:1.10.8.50 - - - 132 270 9.3E-44
Pfam PF06827 Zinc finger found in FPG and IleRS IPR010663 Zinc finger, FPG/IleRS-type 242 269 1.4E-8
CDD cd08966 EcFpg-like_N - - 2 117 4.04265E-53
PANTHER PTHR22993 FORMAMIDOPYRIMIDINE-DNA GLYCOSYLASE - - 1 270 7.6E-48
SUPERFAMILY SSF57716 Glucocorticoid receptor-like (DNA-binding domain) - - 218 269 1.17E-16
FunFam G3DSA:1.10.8.50:FF:000003 Formamidopyrimidine-DNA glycosylase - - 132 270 3.4E-49
Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding 130 220 4.7E-25
Gene3D G3DSA:3.20.190.10 - IPR035937 MutM-like, N-terminal 2 128 5.4E-40
NCBIfam TIGR00577 JCVI: DNA-formamidopyrimidine glycosylase IPR020629 Formamidopyrimidine-DNA glycosylase 1 269 3.9E-91
SMART SM00898 Fapy_DNA_glyco_2 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain 2 116 1.5E-55
Hamap MF_00103 Formamidopyrimidine-DNA glycosylase [mutM]. IPR020629 Formamidopyrimidine-DNA glycosylase 1 270 44.768784
Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain 1 115 5.6E-33

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.