Pseudomonas aeruginosa UCBPP-PA14, PA14_05150 (proC)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0006561 proline biosynthetic process
ISS
Inferred from Sequence or Structural Similarity
Term mapped from: PseudoCAP:PA0393
 ECO:0000249
sequence similarity evidence used in automatic assertion		 8479442
Molecular Function GO:0004735 pyrroline-5-carboxylate reductase activity
ISS
Inferred from Sequence or Structural Similarity
Term mapped from: PseudoCAP:PA0393
 ECO:0000249
sequence similarity evidence used in automatic assertion		 8479442
Molecular Function GO:0004735 pyrroline-5-carboxylate reductase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_01925
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006561 proline biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_01925
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Amino acid biosynthesis and metabolism Other UCBPP-PA14 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pau01230 Biosynthesis of amino acids 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau01110 Biosynthesis of secondary metabolites 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau00330 Arginine and proline metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau01130 Biosynthesis of antibiotics 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
FunFam G3DSA:3.40.50.720:FF:000105 Pyrroline-5-carboxylate reductase - - 1 164 3.7E-60
SUPERFAMILY SSF48179 6-phosphogluconate dehydrogenase C-terminal domain-like IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily 162 270 1.87E-35
FunFam G3DSA:1.10.3730.10:FF:000001 Pyrroline-5-carboxylate reductase - - 166 270 5.4E-35
Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal 5 99 3.8E-23
Gene3D G3DSA:3.40.50.720 - - - 3 164 7.7E-54
PANTHER PTHR11645 PYRROLINE-5-CARBOXYLATE REDUCTASE - - 5 270 2.9E-73
Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. IPR000304 Pyrroline-5-carboxylate reductase 4 267 27.870037
SUPERFAMILY SSF51735 NAD(P)-binding Rossmann-fold domains IPR036291 NAD(P)-binding domain superfamily 5 160 8.86E-40
Gene3D G3DSA:1.10.3730.10 - - - 165 271 1.8E-40
Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain 163 267 5.2E-38
PIRSF PIRSF000193 P5CR IPR000304 Pyrroline-5-carboxylate reductase 3 270 2.7E-83
NCBIfam TIGR00112 JCVI: pyrroline-5-carboxylate reductase IPR000304 Pyrroline-5-carboxylate reductase 6 267 6.9E-80

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.