Pseudomonas aeruginosa UCBPP-PA14, PA14_05250 (pyrC)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0016787 hydrolase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF01979
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004151 dihydroorotase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd01317
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF51338
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006221 pyrimidine nucleotide biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd01317
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0046872 metal ion binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd01317
ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Nucleotide biosynthesis and metabolism Other UCBPP-PA14 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
MetaCyc UMP biosynthesis III InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG pau01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
MetaCyc UMP biosynthesis I InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG pau00240 Pyrimidine metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
MetaCyc UMP biosynthesis II InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Pfam PF01979 Amidohydrolase family IPR006680 Amidohydrolase-related 203 419 6.8E-13
CDD cd01317 DHOase_IIa IPR004722 Dihydroorotase 45 413 0.0
Gene3D G3DSA:2.30.40.10 Urease, subunit C, domain 1 IPR011059 Metal-dependent hydrolase, composite domain superfamily 20 419 2.9E-108
PANTHER PTHR43668 ALLANTOINASE - - 1 420 5.3E-80
NCBIfam TIGR00857 JCVI: dihydroorotase, multifunctional complex type - - 21 421 1.5E-87
SUPERFAMILY SSF51556 Metallo-dependent hydrolases IPR032466 Metal-dependent hydrolase 56 367 2.72E-88
SUPERFAMILY SSF51338 Composite domain of metallo-dependent hydrolases IPR011059 Metal-dependent hydrolase, composite domain superfamily 1 422 4.32E-24
Gene3D G3DSA:3.20.20.140 - - - 57 368 2.9E-108

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.