Pseudomonas aeruginosa UCBPP-PA14, PA14_05390 (chpA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Cellular Component GO:0005737 cytoplasm
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM01231
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016772 transferase activity, transferring phosphorus-containing groups
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00344
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006935 chemotaxis
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF01584
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0016310 phosphorylation
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00344
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004673 protein histidine kinase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM01231
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0007165 signal transduction
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF01584
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0000160 phosphorelay signal transduction system
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd00088
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0000155 phosphorelay sensor kinase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM01231
ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Motility & Attachment Other UCBPP-PA14 genes in this class
Chemotaxis Other UCBPP-PA14 genes in this class
Two-component regulatory systems Other UCBPP-PA14 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pau02020 Two-component system 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau02025 Biofilm formation - Pseudomonas aeruginosa 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
SMART SM00073 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 862 959 1.6E-6
ProSiteProfiles PS50894 Histidine-containing phosphotransfer (HPt) domain profile. IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1035 1141 17.143
SMART SM00387 IPR003594 Histidine kinase/HSP90-like ATPase 2039 2180 1.3E-22
ProSiteProfiles PS50894 Histidine-containing phosphotransfer (HPt) domain profile. IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1526 1626 18.285
ProSiteProfiles PS50110 Response regulatory domain profile. IPR001789 Signal transduction response regulator, receiver domain 2356 2472 43.179
SUPERFAMILY SSF55874 IPR036890 Histidine kinase/HSP90-like ATPase superfamily 1996 2177 7.99E-36
Pfam PF00072 Response regulator receiver domain IPR001789 Signal transduction response regulator, receiver domain 2357 2469 1.4E-27
SUPERFAMILY SSF47226 IPR036641 HPT domain superfamily 1674 1782 4.19E-20
SUPERFAMILY SSF47226 IPR036641 HPT domain superfamily 1360 1482 1.23E-27
SMART SM01231 IPR004105 Histidine kinase CheA-like, homodimeric domain 1855 1994 1.3E-11
CDD cd00088 HPT IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1360 1458 3.18459E-15
Gene3D G3DSA:1.20.120.160 IPR036641 HPT domain superfamily 1518 1653 1.8E-24
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 2140 2158 1.5E-10
SMART SM00073 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1526 1623 0.011
Gene3D G3DSA:1.20.120.160 IPR036641 HPT domain superfamily 861 995 1.6E-25
ProSiteProfiles PS50109 Histidine kinase domain profile. IPR005467 Histidine kinase domain 1947 2180 21.856
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 2084 2098 1.5E-10
Gene3D G3DSA:3.30.565.10 IPR036890 Histidine kinase/HSP90-like ATPase superfamily 1993 2179 7.4E-53
SMART SM00448 IPR001789 Signal transduction response regulator, receiver domain 2355 2468 2.9E-37
SMART SM00073 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1039 1134 0.51
Gene3D G3DSA:2.40.50.180 2203 2277 1.2E-34
Coils Coil 1893 1913 -
SUPERFAMILY SSF52172 IPR011006 CheY-like superfamily 2354 2473 3.98E-36
SUPERFAMILY SSF47226 IPR036641 HPT domain superfamily 1526 1648 1.28E-26
Gene3D G3DSA:1.20.120.160 IPR036641 HPT domain superfamily 14 127 1.4E-6
ProSiteProfiles PS50894 Histidine-containing phosphotransfer (HPt) domain profile. IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1669 1773 19.718
Gene3D G3DSA:3.40.50.12740 2355 2476 1.1E-38
Gene3D G3DSA:1.20.120.160 IPR036641 HPT domain superfamily 1017 1131 2.7E-16
SUPERFAMILY SSF50341 IPR036061 CheW-like domain superfamily 2179 2318 1.7E-21
CDD cd00088 HPT IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1039 1130 1.82787E-5
ProSiteProfiles PS50851 CheW-like domain profile. IPR002545 CheW-like domain 2182 2327 18.831
Pfam PF01627 Hpt domain IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1675 1768 3.7E-15
MobiDBLite mobidb-lite consensus disorder prediction 985 1033 -
Pfam PF01627 Hpt domain IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 864 951 8.6E-14
Gene3D G3DSA:1.20.120.160 IPR036641 HPT domain superfamily 1673 1802 1.1E-20
ProSiteProfiles PS50894 Histidine-containing phosphotransfer (HPt) domain profile. IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1356 1460 19.479
Coils Coil 1756 1783 -
SMART SM00260 IPR002545 CheW-like domain 2172 2322 2.0E-34
Gene3D G3DSA:1.20.120.160 IPR036641 HPT domain superfamily 1356 1484 1.1E-25
Gene3D G3DSA:2.30.30.40 2180 2317 1.2E-34
CDD cd00088 HPT IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1674 1778 5.09247E-13
MobiDBLite mobidb-lite consensus disorder prediction 565 588 -
Gene3D G3DSA:1.20.120.160 IPR036641 HPT domain superfamily 1181 1283 2.2E-6
SUPERFAMILY SSF47226 IPR036641 HPT domain superfamily 7 130 1.44E-23
Pfam PF01627 Hpt domain IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1528 1627 3.5E-14
SUPERFAMILY SSF47226 IPR036641 HPT domain superfamily 1039 1162 2.88E-19
CDD cd00088 HPT IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1526 1624 3.64973E-15
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 2164 2177 1.5E-10
SUPERFAMILY SSF47226 IPR036641 HPT domain superfamily 862 987 7.33E-27
SUPERFAMILY SSF47226 IPR036641 HPT domain superfamily 433 556 1.94E-14
ProSiteProfiles PS50894 Histidine-containing phosphotransfer (HPt) domain profile. IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 858 965 16.055
CDD cd00088 HPT IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 862 958 2.78842E-10
Pfam PF01627 Hpt domain IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1362 1455 4.6E-14
Coils Coil 232 252 -
Pfam PF01584 CheW-like domain IPR002545 CheW-like domain 2185 2324 9.0E-23
Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase IPR003594 Histidine kinase/HSP90-like ATPase 2043 2179 5.5E-16
CDD cd16916 HATPase_CheA-like 2002 2177 9.72887E-84
SUPERFAMILY SSF47226 IPR036641 HPT domain superfamily 1182 1302 3.83E-14
CDD cd00156 REC IPR001789 Signal transduction response regulator, receiver domain 2358 2471 2.05587E-33
Pfam PF01627 Hpt domain IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 10 98 3.5E-8
Coils Coil 1368 1388 -
SMART SM00073 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1360 1457 6.6E-7
Pfam PF01627 Hpt domain IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1041 1127 3.5E-11
SMART SM00073 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1673 1770 6.4E-4

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.