Pseudomonas aeruginosa UCBPP-PA14, PA14_06500 (bioB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0009102 biotin biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_01694
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0051536 iron-sulfur cluster binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00729
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004076 biotin synthase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_01694
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003824 catalytic activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00729
ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Biosynthesis of cofactors, prosthetic groups and carriers Other UCBPP-PA14 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pau00780 Biotin metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Pfam PF04055 Radical SAM superfamily IPR007197 Radical SAM 56 208 7.0E-14
FunFam G3DSA:3.20.20.70:FF:000011 Biotin synthase - - 10 321 0.0
Hamap MF_01694 Biotin synthase [bioB]. IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB 11 319 41.918339
NCBIfam TIGR00433 JCVI: biotin synthase BioB IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB 12 316 5.0E-125
PANTHER PTHR22976 BIOTIN SYNTHASE IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB 5 333 0.0
Pfam PF06968 Biotin and Thiamin Synthesis associated domain IPR010722 Biotin and thiamin synthesis-associated domain 226 316 1.1E-20
SMART SM00729 MiaB IPR006638 Elp3/MiaA/NifB-like, radical SAM core domain 49 261 3.6E-39
SUPERFAMILY SSF102114 Radical SAM enzymes - - 11 320 4.45E-92
Gene3D G3DSA:3.20.20.70 Aldolase class I IPR013785 Aldolase-type TIM barrel 10 321 0.0
PIRSF PIRSF001619 Biotin_synth IPR024177 Biotin synthase 1 325 0.0
SFLD SFLDF00272 biotin synthase IPR024177 Biotin synthase 4 325 0.0
CDD cd01335 Radical_SAM - - 56 255 1.10731E-15
SFLD SFLDG01060 BATS domain containing - - 4 325 0.0
SMART SM00876 BATS_2 IPR010722 Biotin and thiamin synthesis-associated domain 226 318 3.6E-48

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.