Pseudomonas aeruginosa UCBPP-PA14, PA14_07590 (folB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0006760 folic acid-containing compound metabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00526
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004150 dihydroneopterin aldolase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00526
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Biosynthesis of cofactors, prosthetic groups and carriers Other UCBPP-PA14 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pau00790 Folate biosynthesis 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
PANTHER PTHR42844 DIHYDRONEOPTERIN ALDOLASE 1-RELATED IPR006156 Dihydroneopterin aldolase 2 114 1.0E-21
Pfam PF02152 Dihydroneopterin aldolase IPR006157 Dihydroneopterin aldolase/epimerase domain 4 113 7.0E-32
FunFam G3DSA:3.30.1130.10:FF:000002 7,8-dihydroneopterin aldolase - - 1 117 2.7E-47
SMART SM00905 FolB_2 IPR006157 Dihydroneopterin aldolase/epimerase domain 4 114 1.2E-50
NCBIfam TIGR00525 JCVI: dihydroneopterin aldolase IPR006156 Dihydroneopterin aldolase 2 114 2.0E-24
Gene3D G3DSA:3.30.1130.10 - IPR043133 GTP cyclohydrolase I, C-terminal/NADPH-dependent 7-cyano-7-deazaguanine reductase 1 115 6.8E-37
SUPERFAMILY SSF55620 Tetrahydrobiopterin biosynthesis enzymes-like - - 1 115 5.39E-36
NCBIfam TIGR00526 JCVI: FolB domain IPR006157 Dihydroneopterin aldolase/epimerase domain 1 115 1.1E-31
CDD cd00534 DHNA_DHNTPE IPR006157 Dihydroneopterin aldolase/epimerase domain 1 115 3.76587E-29

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.