Pseudomonas aeruginosa UCBPP-PA14, PA14_48040 (aprI)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_48040
Name
aprI
Replicon chromosome
Genomic location 4276883 - 4277278 (- strand)
Transposon Mutants 1 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq YP_791995.1
GI 116049202
Entrez 4385543
INSDC ABJ10438.1
NCBI Locus Tag PA14_48040
UniParc UPI000012D678
UniProtKB Acc Q02J91
UniProtKB ID Q02J91_PSEAB
UniRef100 UniRef100_Q03026
UniRef50 UniRef50_Q03026
UniRef90 UniRef90_Q03026

Product

Feature Type CDS
Coding Frame 1
Product Name
alkaline proteinase inhibitor AprI
Synonyms
Evidence for Translation
Charge (pH 7) -1.89
Kyte-Doolittle Hydrophobicity Value 0.012
Molecular Weight (kDa) 14.0
Isoelectric Point (pI) 5.12

Subcellular localization

Individual Mappings
Localization Confidence PMID
Periplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
1JIW HYDROLASE/HYDROLASE INHIBITOR 07/03/01 Crystal structure of the APR-APRin complex Pseudomonas aeruginosa 1.74 X-RAY DIFFRACTION 100.0
2RN4 HYDROLASE INHIBITOR 12/06/07 Solution structure of the alkaline proteinase inhibitor APRin from Pseudomonas aeruginosa Pseudomonas aeruginosa NOT SOLUTION NMR 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 7 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001202 (325 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_48040
Search term: aprI

Human Homologs

References

No references are associated with this feature.