Pseudomonas aeruginosa UCBPP-PA14, PA14_48060 (aprA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14
GCF_000014625.1|latest
Locus Tag
PA14_48060
Name
aprA
Replicon chromosome
Genomic location 4277525 - 4278964 (- strand)
Transposon Mutants 1 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 8 transposon mutants in orthologs

Cross-References

RefSeq YP_791996.1
GI 116049201
Entrez 4385542
INSDC ABJ10437.1
NCBI Locus Tag PA14_48060
UniParc UPI0000E44B45
UniProtKB Acc Q02J90
UniProtKB ID Q02J90_PSEAB
UniRef100 UniRef100_Q02J90
UniRef50 UniRef50_Q03023
UniRef90 UniRef90_Q03023

Product

Feature Type CDS
Coding Frame 1
Product Name
alkaline metalloproteinase
Synonyms
Evidence for Translation
Charge (pH 7) -29.31
Kyte-Doolittle Hydrophobicity Value -0.216
Molecular Weight (kDa) 50.4
Isoelectric Point (pI) 4.06

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 3
Additional evidence for subcellular localization

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
1JIW HYDROLASE/HYDROLASE INHIBITOR 07/03/01 Crystal structure of the APR-APRin complex PSEUDOMONAS AERUGINOSA 1.74 X-RAY DIFFRACTION 99.6
1AKL HYDROLASE (METALLOPROTEINASE) 09/16/95 ALKALINE PROTEASE FROM PSEUDOMONAS AERUGINOSA IFO3080 PSEUDOMONAS AERUGINOSA 2.0 X-RAY DIFFRACTION 99.6
1KAP ZINC METALLOPROTEASE 06/08/95 THREE-DIMENSIONAL STRUCTURE OF THE ALKALINE PROTEASE OF PSEUDOMONAS AERUGINOSA: A TWO-DOMAIN PROTEIN WITH A CALCIUM BINDING PARALLEL BETA ROLL MOTIF PSEUDOMONAS AERUGINOSA 1.64 X-RAY DIFFRACTION 99.6
3VI1 HYDROLASE 09/13/11 Crystal structure of Pseudomonas aerginosa alkaline protease complexed with Substance P(1-6) PSEUDOMONAS AERUGINOSA; SYNTHETIC CONSTRUCT 2.0 X-RAY DIFFRACTION 99.6

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 128 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001201 (1306 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_48060
Search term: aprA

References

No references are associated with this feature.