Pseudomonas aeruginosa UCBPP-PA14, PA14_49560 (toxA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0047286 NAD+-diphthamide ADP-ribosyltransferase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF09009
ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Secreted Factors (toxins, enzymes, alginate) Other UCBPP-PA14 genes in this class

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Gene3D G3DSA:2.60.120.200 - - - 26 255 9.1E-115
Pfam PF09101 Exotoxin A binding IPR015185 Exotoxin A, binding 27 275 4.2E-121
Pfam PF09009 Exotoxin A catalytic IPR015099 Exotoxin A catalytic domain 444 615 1.3E-100
MobiDBLite mobidb-lite consensus disorder prediction - - 593 635 -
CDD cd01436 Dipth_tox_like IPR015099 Exotoxin A catalytic domain 459 591 4.03918E-67
Pfam PF09102 Exotoxin A, targeting IPR015186 Exotoxin A, middle domain 277 406 5.2E-67
Gene3D G3DSA:3.90.1350.10 Exotoxin A, middle domain IPR036478 Exotoxin A, middle domain superfamily 266 420 2.0E-74
SUPERFAMILY SSF49899 Concanavalin A-like lectins/glucanases IPR013320 Concanavalin A-like lectin/glucanase domain superfamily 27 276 0.0
Gene3D G3DSA:3.90.175.10 Diphtheria Toxin, domain 1 - - 421 627 8.6E-90
SUPERFAMILY SSF56864 Exotoxin A, middle domain IPR036478 Exotoxin A, middle domain superfamily 277 416 5.23E-66
SUPERFAMILY SSF56399 ADP-ribosylation - - 417 628 3.05E-79

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.