Pseudomonas aeruginosa UCBPP-PA14, PA14_51270 (dapA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0009089 lysine biosynthetic process via diaminopimelate
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd00950
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0008840 4-hydroxy-tetrahydrodipicolinate synthase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd00950
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016829 lyase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PTHR12128
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Amino acid biosynthesis and metabolism Other UCBPP-PA14 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pau01130 Biosynthesis of antibiotics 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau01110 Biosynthesis of secondary metabolites 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau00300 Lysine biosynthesis 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCAP Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; tetrahydrodipicolinate from L-aspartate: step 3 ECO:0000037
not_recorded
PseudoCAP Lysine biosynthesis ECO:0000037
not_recorded
KEGG pau00261 Monobactam biosynthesis 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau01230 Biosynthesis of amino acids 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau01120 Microbial metabolism in diverse environments 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
PIRSF PIRSF001365 DHDPS IPR002220 DapA-like 1 292 1.9E-100
SUPERFAMILY SSF51569 Aldolase - - 2 289 3.87E-107
CDD cd00950 DHDPS IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA 4 285 0.0
Pfam PF00701 Dihydrodipicolinate synthetase family IPR002220 DapA-like 2 285 1.7E-109
PRINTS PR00146 Dihydrodipicolinate synthase signature IPR002220 DapA-like 103 119 8.9E-35
PRINTS PR00146 Dihydrodipicolinate synthase signature IPR002220 DapA-like 35 56 8.9E-35
Gene3D G3DSA:3.20.20.70 Aldolase class I IPR013785 Aldolase-type TIM barrel 1 291 9.8E-111
PRINTS PR00146 Dihydrodipicolinate synthase signature IPR002220 DapA-like 71 89 8.9E-35
SMART SM01130 DHDPS_2 IPR002220 DapA-like 1 289 0.0
NCBIfam TIGR00674 JCVI: 4-hydroxy-tetrahydrodipicolinate synthase IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA 5 286 3.3E-115
PRINTS PR00146 Dihydrodipicolinate synthase signature IPR002220 DapA-like 128 145 8.9E-35
PANTHER PTHR12128 DIHYDRODIPICOLINATE SYNTHASE IPR002220 DapA-like 3 290 1.0E-81
Coils Coil Coil - - 160 180 -
Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA 1 287 69.373184

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.