Pseudomonas aeruginosa UCBPP-PA14, PA14_51330 (nadA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0051539 4 iron, 4 sulfur cluster binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:3.40.50.10800
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00567
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0008987 quinolinate synthetase A activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:3.40.50.10800
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0009435 NAD biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:3.40.50.10800
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Amino acid biosynthesis and metabolism Other UCBPP-PA14 genes in this class
Biosynthesis of cofactors, prosthetic groups and carriers Other UCBPP-PA14 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pau01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau00760 Nicotinate and nicotinamide metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
PANTHER PTHR30573 QUINOLINATE SYNTHETASE A IPR003473 Quinolinate synthetase A 10 348 1.9E-78
Gene3D G3DSA:3.40.50.10800 - IPR036094 Quinolinate synthetase A superfamily 201 296 5.7E-96
SUPERFAMILY SSF142754 NadA-like IPR036094 Quinolinate synthetase A superfamily 31 340 1.29E-109
Gene3D G3DSA:3.40.50.10800 - IPR036094 Quinolinate synthetase A superfamily 116 338 5.7E-96
NCBIfam TIGR00550 JCVI: quinolinate synthase IPR003473 Quinolinate synthetase A 30 341 1.9E-110
Gene3D G3DSA:3.40.50.10800 - IPR036094 Quinolinate synthetase A superfamily 36 321 5.7E-96
Hamap MF_00567 Quinolinate synthase [nadA]. IPR023513 Quinolinate synthase A, type 1 1 346 70.7481
Pfam PF02445 Quinolinate synthetase A protein IPR003473 Quinolinate synthetase A 34 339 5.6E-106
FunFam G3DSA:3.40.50.10800:FF:000001 Quinolinate synthase A - - 201 296 1.8E-36

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.