Pseudomonas aeruginosa UCBPP-PA14, PA14_51790 (ruvA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Cellular Component GO:0009379 Holliday junction helicase complex
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF07499
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003678 DNA helicase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00031
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0005524 ATP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF01330
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0009378 four-way junction helicase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF01330
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006310 DNA recombination
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF01330
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006281 DNA repair
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF01330
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003677 DNA binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00278
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

DNA replication, recombination, modification and repair Other UCBPP-PA14 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pau03440 Homologous recombination 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Pfam PF07499 RuvA, C-terminal domain IPR011114 Holliday junction DNA helicase RuvA, C-terminal 157 200 1.4E-15
SUPERFAMILY SSF47781 RuvA domain 2-like IPR010994 RuvA domain 2-like 66 137 2.54E-22
Pfam PF01330 RuvA N terminal domain IPR013849 DNA helicase, Holliday junction RuvA type, domain I, bacterial 1 62 2.4E-24
Hamap MF_00031 Holliday junction branch migration complex subunit RuvA [ruvA]. IPR000085 Holliday junction branch migration complex subunit RuvA 1 201 32.171883
Gene3D G3DSA:1.10.8.10 - - - 155 201 1.3E-18
Gene3D G3DSA:1.10.150.20 - - - 67 140 3.5E-29
Coils Coil Coil - - 118 138 -
CDD cd14332 UBA_RuvA_C IPR011114 Holliday junction DNA helicase RuvA, C-terminal 156 198 1.10073E-11
SMART SM00278 HhH1_4 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 73 92 0.72
Gene3D G3DSA:2.40.50.140 - IPR012340 Nucleic acid-binding, OB-fold 1 66 2.5E-28
SMART SM00278 HhH1_4 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 108 127 0.017
Pfam PF14520 Helix-hairpin-helix domain - - 72 130 4.4E-18
SUPERFAMILY SSF46929 DNA helicase RuvA subunit, C-terminal domain IPR036267 RuvA, C-terminal domain superfamily 156 200 1.2E-10
SUPERFAMILY SSF50249 Nucleic acid-binding proteins IPR012340 Nucleic acid-binding, OB-fold 1 63 6.85E-20
NCBIfam TIGR00084 JCVI: Holliday junction branch migration protein RuvA IPR000085 Holliday junction branch migration complex subunit RuvA 1 199 3.2E-61

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.