Pseudomonas aeruginosa UCBPP-PA14, PA14_51900 (proS)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_51900
Name
proS
Replicon chromosome
Genomic location 4608130 - 4609845 (+ strand)

Cross-References

RefSeq YP_792318.1
GI 116048881
EC Number 6.1.1.15
Entrez 4380034
INSDC ABJ10117.1
NCBI Locus Tag PA14_51900
UniParc UPI000045D07F
UniProtKB Acc Q02IB8
UniProtKB ID SYP_PSEAB
UniRef100 UniRef100_Q02IB8
UniRef50 UniRef50_P43830
UniRef90 UniRef90_B7UXX6

Product

Feature Type CDS
Coding Frame 1
Product Name
prolyl-tRNA synthetase
Synonyms
Evidence for Translation
Charge (pH 7) -15.16
Kyte-Doolittle Hydrophobicity Value -0.208
Molecular Weight (kDa) 63.2
Isoelectric Point (pI) 5.09

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
5UCM LIGASE 12/22/16 Crystal Structure of Prolyl-tRNA Synthetase from Pseudomonas aeruginosa Pseudomonas aeruginosa 2.6 X-RAY DIFFRACTION 99.5

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 665 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000922 (533 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_51900
Search term: proS

Human Homologs

Ensembl 110, assembly GRCh38.p14
prolyl-tRNA synthetase 2, mitochondrial [Source:HGNC Symbol;Acc:HGNC:30563]
E-value: 7.0e-66
Percent Identity: 32.3

References

No references are associated with this feature.