Pseudomonas aeruginosa UCBPP-PA14, PA14_52600 (alaS)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0006419 alanyl-tRNA aminoacylation
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PS50860
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004813 alanine-tRNA ligase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00036_B
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0000166 nucleotide binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF55186
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Cellular Component GO:0005737 cytoplasm
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00344
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004812 aminoacyl-tRNA ligase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF07973
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0005524 ATP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PS50860
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0043039 tRNA aminoacylation
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF07973
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003676 nucleic acid binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PS50860
ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Transcription, RNA processing and degradation Other UCBPP-PA14 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG (InterPro) 00970 Aminoacyl-tRNA biosynthesis InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG pau00970 Aminoacyl-tRNA biosynthesis 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
SUPERFAMILY SSF101353 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain superfamily 254 452 6.02E-63
Gene3D G3DSA:3.30.54.20 622 676 2.9E-52
Coils Coil 607 627 -
Coils Coil 706 758 -
SUPERFAMILY SSF55186 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily 550 706 7.59E-52
Hamap MF_00036_B Alanine--tRNA ligase [alaS]. IPR023033 Alanine-tRNA ligase, eukaryota/bacteria 1 874 208.98
TIGRFAM TIGR00344 alaS: alanine--tRNA ligase IPR002318 Alanine-tRNA ligase, class IIc 5 853 0.0
PRINTS PR00980 Alanyl-tRNA synthetase signature IPR002318 Alanine-tRNA ligase, class IIc 304 317 4.1E-31
Gene3D G3DSA:2.40.30.130 473 550 1.1E-11
PRINTS PR00980 Alanyl-tRNA synthetase signature IPR002318 Alanine-tRNA ligase, class IIc 74 85 4.1E-31
Gene3D G3DSA:3.10.310.40 763 871 1.1E-29
Coils Coil 366 386 -
PRINTS PR00980 Alanyl-tRNA synthetase signature IPR002318 Alanine-tRNA ligase, class IIc 280 296 4.1E-31
CDD cd00673 AlaRS_core 3 249 1.07494E-134
Pfam PF01411 tRNA synthetases class II (A) IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal 5 552 0.0
PRINTS PR00980 Alanyl-tRNA synthetase signature IPR002318 Alanine-tRNA ligase, class IIc 207 218 4.1E-31
ProSiteProfiles PS50860 Alanyl-transfer RNA synthetases family profile. IPR018165 Alanyl-tRNA synthetase, class IIc, core domain 1 708 132.966
Pfam PF02272 DHHA1 domain IPR003156 DHHA1 domain 732 870 1.3E-27
Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain IPR012947 Threonyl/alanyl tRNA synthetase, SAD 651 695 4.3E-19
SMART SM00863 IPR012947 Threonyl/alanyl tRNA synthetase, SAD 651 695 8.2E-23
Gene3D G3DSA:3.30.930.10 1 250 3.5E-122
PRINTS PR00980 Alanyl-tRNA synthetase signature IPR002318 Alanine-tRNA ligase, class IIc 234 247 4.1E-31
SUPERFAMILY SSF50447 IPR009000 Translation protein, beta-barrel domain superfamily 452 550 1.24E-19
Gene3D G3DSA:3.30.980.10 561 696 2.9E-52
SUPERFAMILY SSF55681 2 253 7.46E-107

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.