Pseudomonas aeruginosa UCBPP-PA14, PA14_52990 (phhA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0009072 aromatic amino acid family metabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:1.10.800.10
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00372
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0055114 oxidation-reduction process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:1.10.800.10
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0005506 iron ion binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:1.10.800.10
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004497 monooxygenase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:1.10.800.10
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004505 phenylalanine 4-monooxygenase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01267
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006559 L-phenylalanine catabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01267
ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Amino acid biosynthesis and metabolism Other UCBPP-PA14 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pau00360 Phenylalanine metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCAP Phenylalanine, tyrosine and tryptophan biosynthesis  ECO:0000037
not_recorded
KEGG pau01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau01230 Biosynthesis of amino acids 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau00400 Phenylalanine, tyrosine and tryptophan biosynthesis 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
ProSiteProfiles PS51410 Biopterin-dependent aromatic amino acid hydroxylase family profile. IPR019774 Aromatic amino acid hydroxylase, C-terminal 1 262 103.179
TIGRFAM TIGR01267 Phe4hydrox_mono: phenylalanine-4-hydroxylase IPR005960 Phenylalanine-4-hydroxylase, monomeric form 9 254 0.0
PRINTS PR00372 Biopterin-dependent aromatic amino acid hydroxylase signature IPR019774 Aromatic amino acid hydroxylase, C-terminal 74 96 1.9E-9
SUPERFAMILY SSF56534 IPR036329 Aromatic amino acid monoxygenase, C-terminal domain superfamily 3 248 4.58E-101
Gene3D G3DSA:1.10.800.10 IPR036951 Aromatic amino acid hydroxylase superfamily 1 262 1.2E-103
CDD cd03348 pro_PheOH IPR005960 Phenylalanine-4-hydroxylase, monomeric form 9 233 7.38606E-127
ProSitePatterns PS00367 Biopterin-dependent aromatic amino acid hydroxylases signature. IPR018301 Aromatic amino acid hydroxylase, iron/copper binding site 117 128 -
PRINTS PR00372 Biopterin-dependent aromatic amino acid hydroxylase signature IPR019774 Aromatic amino acid hydroxylase, C-terminal 178 196 1.9E-9
Pfam PF00351 Biopterin-dependent aromatic amino acid hydroxylase IPR019774 Aromatic amino acid hydroxylase, C-terminal 15 229 5.4E-47
PRINTS PR00372 Biopterin-dependent aromatic amino acid hydroxylase signature IPR019774 Aromatic amino acid hydroxylase, C-terminal 138 157 1.9E-9
PRINTS PR00372 Biopterin-dependent aromatic amino acid hydroxylase signature IPR019774 Aromatic amino acid hydroxylase, C-terminal 209 228 1.9E-9

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.