Strain |
Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest |
Locus Tag |
PA14_53940
|
Name |
prpB
|
Replicon | chromosome |
Genomic location | 4782285 - 4783181 (+ strand) |
Transposon Mutants | 2 transposon mutants in UCBPP-PA14 |
Transposon Mutants in orthologs | 3 transposon mutants in orthologs |
RefSeq | YP_792486.1 |
GI | 116048714 |
EC Number | 4.1.3.30 |
Entrez | 4381663 |
INSDC | ABJ09950.1 |
NCBI Locus Tag | PA14_53940 |
UniParc | UPI00000C5159 |
UniProtKB Acc | Q02HV0 |
UniProtKB ID | Q02HV0_PSEAB |
UniRef100 | UniRef100_W0YNY4 |
UniRef50 | UniRef50_Q56062 |
UniRef90 | UniRef90_W0YNY4 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
2-methylisocitrate lyase
|
Synonyms | |
Evidence for Translation | |
Charge (pH 7) | -5.92 |
Kyte-Doolittle Hydrophobicity Value | 0.032 |
Molecular Weight (kDa) | 32.1 |
Isoelectric Point (pI) | 5.20 |
Individual Mappings | |
Additional evidence for subcellular localization |
Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
6T4V | LYASE | 10/15/19 | Crystal structure of 2-methylisocitrate lyase (PrpB) from Pseudomonas aeruginosa in apo form. | Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) | 1.807 | X-RAY DIFFRACTION | 100.0 |
6T5M | LYASE | 10/16/19 | Crystal structure of 2-methylisocitrate lyase (PrpB) from Pseudomonas aeruginosa in complex with Mg(II)-pyruvate. | Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) | 1.76 | X-RAY DIFFRACTION | 100.0 |
Source 1 | |
Database | PseudoCAP |
Category | |
Evidence |
ECO:0000015
mutant phenotype evidence
|
Host Organism | Caenorhabditis elegans |
Notes | |
Infection model | C. elegans slow killing assay. |
Reference | 22911607 |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 342 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG000769 (537 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA14_53940
Search term: prpB
Search term: 2-methylisocitrate lyase
|