Pseudomonas aeruginosa UCBPP-PA14, PA14_54170 (putA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_54170
Name
putA
Replicon chromosome
Genomic location 4802984 - 4806166 (- strand)
Transposon Mutants 2 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 3 transposon mutants in orthologs

Cross-References

RefSeq YP_792502.1
GI 116048698
EC Number 1.5.1.12
EC Number 1.5.99.8
EC Number 1.2.1.88
EC Number 1.5.5.2
Entrez 4384731
INSDC ABJ09934.1
NCBI Locus Tag PA14_54170
UniParc UPI000045D03C
UniProtKB Acc Q02HT4
UniProtKB ID Q02HT4_PSEAB
UniRef100 UniRef100_Q02HT4
UniRef50 UniRef50_Q9I5F6
UniRef90 UniRef90_Q9I5F6

Product

Feature Type CDS
Coding Frame 1
Product Name
bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase
Synonyms
Evidence for Translation
Charge (pH 7) -10.17
Kyte-Doolittle Hydrophobicity Value -0.120
Molecular Weight (kDa) 115.6
Isoelectric Point (pI) 6.02

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 594 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000756 (535 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_54170
Search term: putA

Human Homologs

Ensembl 110, assembly GRCh38.p14
aldehyde dehydrogenase 8 family member A1 [Source:HGNC Symbol;Acc:HGNC:15471]
E-value: 5.5e-32
Percent Identity: 28.5

References

No references are associated with this feature.