Pseudomonas aeruginosa UCBPP-PA14, PA14_55430 (hxcS)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_55430
Name
hxcS
Replicon chromosome
Genomic location 4932324 - 4933538 (- strand)
Transposon Mutants in orthologs 5 transposon mutants in orthologs

Cross-References

RefSeq YP_792607.1
GI 116048594
Entrez 4382534
INSDC ABJ09830.1
NCBI Locus Tag PA14_55430
UniParc UPI0000396480
UniProtKB Acc Q02HH9
UniProtKB ID Q02HH9_PSEAB
UniRef100 UniRef100_W0Z2U7
UniRef50 UniRef50_D5CMQ1
UniRef90 UniRef90_A6VAS9

Product

Feature Type CDS
Coding Frame 1
Product Name
HxcS
Product Name Confidence: Class 1
Synonyms type II secretion system protein
Evidence for Translation
Charge (pH 7) 4.67
Kyte-Doolittle Hydrophobicity Value 0.241
Molecular Weight (kDa) 43.4
Isoelectric Point (pI) 9.42

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 399 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000666 (814 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_55430
Search term: hxcS
Search term: HxcS

Human Homologs

References

A novel type II secretion system in Pseudomonas aeruginosa.
Ball G, Durand E, Lazdunski A, Filloux A
Mol Microbiol 2002 Jan;43(2):475-85
PubMed ID: 11985723