Pseudomonas aeruginosa UCBPP-PA14, PA14_58350 (dppA1)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_58350
Name
dppA1
Replicon chromosome
Genomic location 5195069 - 5196682 (+ strand)
Transposon Mutants 2 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 6 transposon mutants in orthologs
Comment

Cross-References

RefSeq YP_792841.1
GI 116052528
Entrez 4382618
INSDC ABJ13764.1
NCBI Locus Tag PA14_58350
UniParc UPI0000E44BE5
UniProtKB Acc Q02GU5
UniProtKB ID Q02GU5_PSEAB
UniRef100 UniRef100_S0IPR2
UniRef50 UniRef50_Q4KIC0
UniRef90 UniRef90_V6ALT5

Product

Feature Type CDS
Coding Frame 1
Product Name
dipeptide ABC transporter substrate-binding protein DppA1
Product Name Confidence: Class 1
Synonyms ABC transporter substrate-binding protein
Evidence for Translation
Charge (pH 7) 1.06
Kyte-Doolittle Hydrophobicity Value -0.469
Molecular Weight (kDa) 60.1
Isoelectric Point (pI) 7.28

Subcellular localization

Individual Mappings
Localization Confidence PMID
Periplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 560 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004084 (810 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_58350
Search term: dppA1

Human Homologs

References

High-throughput screening of dipeptide utilization mediated by the ABC transporter DppBCDF and its substrate-binding proteins DppA1-A5 in Pseudomonas aeruginosa.
Pletzer D, Lafon C, Braun Y, Köhler T, Page MG, Mourez M, Weingart H
PLoS One 2014;9(10):e111311
PubMed ID: 25338022
Substrate Binding Protein DppA1 of ABC Transporter DppBCDF Increases Biofilm Formation in Pseudomonas aeruginosa by Inhibiting Pf5 Prophage Lysis.
Lee Y, Song S, Sheng L, Zhu L, Kim JS, Wood TK
Front Microbiol 2018;9:30
PubMed ID: 29416528