Pseudomonas aeruginosa UCBPP-PA14, PA14_71460 (glyA1)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0004372 glycine hydroxymethyltransferase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd00378
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0019264 glycine biosynthetic process from serine
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd00378
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0030170 pyridoxal phosphate binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd00378
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0035999 tetrahydrofolate interconversion
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd00378
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Amino acid biosynthesis and metabolism Other UCBPP-PA14 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pau01130 Biosynthesis of antibiotics 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau00460 Cyanoamino acid metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau00260 Glycine, serine and threonine metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau00670 One carbon pool by folate 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau00630 Glyoxylate and dicarboxylate metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau01200 Carbon metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau00680 Methane metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau01120 Microbial metabolism in diverse environments 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau01230 Biosynthesis of amino acids 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau01110 Biosynthesis of secondary metabolites 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
FunFam G3DSA:3.40.640.10:FF:000001 Serine hydroxymethyltransferase - - 37 280 0.0
FunFam G3DSA:3.90.1150.10:FF:000003 Serine hydroxymethyltransferase - - 276 416 1.8E-59
PANTHER PTHR11680 SERINE HYDROXYMETHYLTRANSFERASE IPR001085 Serine hydroxymethyltransferase 7 388 0.0
Gene3D G3DSA:3.90.1150.10 Aspartate Aminotransferase, domain 1 IPR015422 Pyridoxal phosphate-dependent transferase, small domain 11 416 0.0
Gene3D G3DSA:3.40.640.10 - IPR015421 Pyridoxal phosphate-dependent transferase, major domain 37 280 0.0
Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. IPR001085 Serine hydroxymethyltransferase 7 417 53.065945
SUPERFAMILY SSF53383 PLP-dependent transferases IPR015424 Pyridoxal phosphate-dependent transferase 7 416 0.0
Pfam PF00464 Serine hydroxymethyltransferase IPR039429 Serine hydroxymethyltransferase-like domain 11 386 0.0
PIRSF PIRSF000412 SHMT IPR001085 Serine hydroxymethyltransferase 1 415 0.0
CDD cd00378 SHMT IPR001085 Serine hydroxymethyltransferase 11 409 0.0

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.