Pseudomonas aeruginosa UCBPP-PA14, PA14_72540

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0000166 nucleotide binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd02888
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd02888
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0031419 cobalamin binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd02888
ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Nucleotide biosynthesis and metabolism Other UCBPP-PA14 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pau00240 Pyrimidine metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau00230 Purine metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
PRINTS PR01183 Ribonucleotide reductase large chain signature IPR000788 Ribonucleotide reductase large subunit, C-terminal 440 463 2.6E-18
PRINTS PR01183 Ribonucleotide reductase large chain signature IPR000788 Ribonucleotide reductase large subunit, C-terminal 197 216 2.6E-18
PANTHER PTHR43371 VITAMIN B12-DEPENDENT RIBONUCLEOTIDE REDUCTASE - - 15 725 0.0
SUPERFAMILY SSF51998 PFL-like glycyl radical enzymes - - 35 710 0.0
CDD cd02888 RNR_II_dimer IPR013344 Ribonucleotide reductase, adenosylcobalamin-dependent 95 671 0.0
PRINTS PR01183 Ribonucleotide reductase large chain signature IPR000788 Ribonucleotide reductase large subunit, C-terminal 528 555 2.6E-18
PRINTS PR01183 Ribonucleotide reductase large chain signature IPR000788 Ribonucleotide reductase large subunit, C-terminal 336 347 2.6E-18
NCBIfam TIGR02504 JCVI: adenosylcobalamin-dependent ribonucleoside-diphosphate reductase IPR013344 Ribonucleotide reductase, adenosylcobalamin-dependent 43 678 0.0
FunFam G3DSA:3.20.70.20:FF:000040 Vitamin B12-dependent ribonucleotide reductase - - 14 672 0.0
PRINTS PR01183 Ribonucleotide reductase large chain signature IPR000788 Ribonucleotide reductase large subunit, C-terminal 374 397 2.6E-18
Pfam PF02867 Ribonucleotide reductase, barrel domain IPR000788 Ribonucleotide reductase large subunit, C-terminal 123 669 0.0
Gene3D G3DSA:3.20.70.20 - - - 14 672 0.0
PRINTS PR01183 Ribonucleotide reductase large chain signature IPR000788 Ribonucleotide reductase large subunit, C-terminal 412 434 2.6E-18

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.