Pseudomonas sp. UW4, PputUW4_03390 (thrS1)
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Ontology
| Ontology | Accession | Term | GO Evidence | Evidence Ontology (ECO) Code | Reference | Comments |
|---|---|---|---|---|---|---|
| Molecular Function | GO:0000166 | nucleotide binding |
Inferred from Sequence Model
Term mapped from: InterPro:SSF55186
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
| Molecular Function | GO:0004829 | threonine-tRNA ligase activity |
Inferred from Sequence Model
Term mapped from: InterPro:MF_00184
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
| Biological Process | GO:0006418 | tRNA aminoacylation for protein translation |
Inferred from Sequence Model
Term mapped from: InterPro:PF00587
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
| Molecular Function | GO:0004812 | aminoacyl-tRNA ligase activity |
Inferred from Sequence Model
Term mapped from: InterPro:PF07973
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
| Cellular Component | GO:0005737 | cytoplasm |
Inferred from Sequence Model
Term mapped from: InterPro:MF_00184
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
| Molecular Function | GO:0005524 | ATP binding |
Inferred from Sequence Model
Term mapped from: InterPro:MF_00184
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
| Biological Process | GO:0006435 | threonyl-tRNA aminoacylation |
Inferred from Sequence Model
Term mapped from: InterPro:MF_00184
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
| Biological Process | GO:0043039 | tRNA aminoacylation |
Inferred from Sequence Model
Term mapped from: InterPro:PF07973
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
Functional Classifications Manually Assigned by PseudoCAP
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Pathways
| Database | Xref | Pathway | Version | Evidence | PMID |
|---|---|---|---|---|---|
| KEGG | ppuu00970 | Aminoacyl-tRNA biosynthesis | 81.0+/01-23, Jan 17 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
Functional Predictions from Interpro
| Analysis | Accession | Description | Interpro Accession | Interpro Description | Amino Acid Start | Amino Acid Stop | E-value |
|---|---|---|---|---|---|---|---|
| PRINTS | PR01047 | Threonyl-tRNA synthetase signature | IPR002320 | Threonine-tRNA ligase, class IIa | 328 | 356 | 7.2E-53 |
| PRINTS | PR01047 | Threonyl-tRNA synthetase signature | IPR002320 | Threonine-tRNA ligase, class IIa | 506 | 519 | 7.2E-53 |
| Pfam | PF00587 | tRNA synthetase class II core domain (G, H, P, S and T) | IPR002314 | Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) | 317 | 528 | 2.5E-44 |
| SUPERFAMILY | SSF52954 | Class II aaRS ABD-related | - | - | 528 | 632 | 3.93E-30 |
| SUPERFAMILY | SSF81271 | TGS-like | IPR012676 | TGS-like | 3 | 61 | 2.84E-15 |
| NCBIfam | TIGR00418 | JCVI: threonine--tRNA ligase | IPR002320 | Threonine-tRNA ligase, class IIa | 72 | 629 | 0.0 |
| CDD | cd01667 | TGS_ThrRS | - | - | 2 | 66 | 1.3682E-25 |
| Gene3D | G3DSA:3.30.930.10 | Bira Bifunctional Protein; Domain 2 | IPR045864 | Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) | 222 | 530 | 0.0 |
| SUPERFAMILY | SSF55186 | ThrRS/AlaRS common domain | IPR018163 | Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily | 63 | 240 | 1.27E-63 |
| PRINTS | PR01047 | Threonyl-tRNA synthetase signature | IPR002320 | Threonine-tRNA ligase, class IIa | 533 | 545 | 7.2E-53 |
| PANTHER | PTHR11451 | THREONINE-TRNA LIGASE | - | - | 3 | 633 | 0.0 |
| Gene3D | G3DSA:3.30.54.20 | - | - | - | 130 | 186 | 1.8E-62 |
| Pfam | PF07973 | Threonyl and Alanyl tRNA synthetase second additional domain | IPR012947 | Threonyl/alanyl tRNA synthetase, SAD | 172 | 218 | 2.1E-13 |
| FunFam | G3DSA:3.40.50.800:FF:000001 | Threonine--tRNA ligase | - | - | 531 | 637 | 5.3E-37 |
| Hamap | MF_00184 | Threonine--tRNA ligase [thrS]. | IPR002320 | Threonine-tRNA ligase, class IIa | 66 | 633 | 34.158554 |
| PRINTS | PR01047 | Threonyl-tRNA synthetase signature | IPR002320 | Threonine-tRNA ligase, class IIa | 463 | 491 | 7.2E-53 |
| CDD | cd00771 | ThrRS_core | IPR033728 | Threonine-tRNA ligase catalytic core domain | 241 | 538 | 0.0 |
| Pfam | PF02824 | TGS domain | IPR004095 | TGS | 4 | 61 | 1.1E-9 |
| FunFam | G3DSA:3.30.980.10:FF:000005 | Threonyl-tRNA synthetase, mitochondrial | - | - | 65 | 222 | 1.1E-39 |
| Gene3D | G3DSA:3.30.980.10 | - | - | - | 68 | 221 | 1.8E-62 |
| Gene3D | G3DSA:3.10.20.30 | - | IPR012675 | Beta-grasp domain superfamily | 1 | 64 | 2.9E-26 |
| SUPERFAMILY | SSF55681 | Class II aaRS and biotin synthetases | IPR045864 | Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) | 242 | 525 | 1.76E-102 |
| Pfam | PF03129 | Anticodon binding domain | IPR004154 | Anticodon-binding | 540 | 628 | 4.0E-20 |
| FunFam | G3DSA:3.30.54.20:FF:000002 | Threonine--tRNA ligase | - | - | 130 | 186 | 9.5E-23 |
| SMART | SM00863 | tRNA_SAD_4 | IPR012947 | Threonyl/alanyl tRNA synthetase, SAD | 169 | 218 | 3.6E-20 |
| PRINTS | PR01047 | Threonyl-tRNA synthetase signature | IPR002320 | Threonine-tRNA ligase, class IIa | 361 | 384 | 7.2E-53 |
| FunFam | G3DSA:3.10.20.30:FF:000005 | Threonine--tRNA ligase | - | - | 1 | 64 | 4.6E-29 |
| CDD | cd00860 | ThrRS_anticodon | IPR047246 | Threonine-tRNA ligase, class IIa, anticodon-binding domain | 538 | 627 | 1.94256E-37 |
| Gene3D | G3DSA:3.40.50.800 | - | IPR036621 | Anticodon-binding domain superfamily | 531 | 639 | 2.1E-31 |
| FunFam | G3DSA:3.30.930.10:FF:000002 | Threonine--tRNA ligase | - | - | 224 | 531 | 0.0 |
Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.