Pseudomonas aeruginosa PAO1, PA0005 (lptA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag
PA0005
Name
lptA
Synonym: plsC
Replicon chromosome
Genomic location 7018 - 7791 (- strand)
Transposon Mutants 2 transposon mutants in PAO1

Cross-References

RefSeq NP_064725.1
GI 15595203
Affymetrix PA0005_at
Entrez 877576
GenBank AAG03395.1
INSDC AAG03395.1
NCBI Locus Tag PA0005
protein_id(GenBank) gb|AAG03395.1|AE004440_5|gnl|PseudoCAP|PA0005
TIGR NTL03PA00006
UniParc UPI00000C4EE2
UniProtKB Acc Q9I7C1
UniProtKB ID Q9I7C1_PSEAE
UniRef100 UniRef100_Q9I7C1
UniRef50 UniRef50_Q9I7C1
UniRef90 UniRef90_Q9I7C1

Product

Feature Type CDS
Coding Frame 1
Product Name
lysophosphatidic acid acyltransferase, LptA
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 10.86
Kyte-Doolittle Hydrophobicity Value 0.182
Molecular Weight (kDa) 28.7
Isoelectric Point (pI) 10.23

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 465 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000005 (555 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0005
Search term: lptA

References

Modulation of quorum sensing in Pseudomonas aeruginosa through alteration of membrane properties.
Baysse C, Cullinane M, Dénervaud V, Burrowes E, Dow JM, Morrissey JP, Tam L, Trevors JT, O'Gara F
Microbiology (Reading, Engl.) 2005 Aug;151(Pt 8):2529-42
PubMed ID: 16079332
cDNA cloning and expression of murine 1-acyl-sn-glycerol-3-phosphate acyltransferase.
Kume K, Shimizu T
Biochem. Biophys. Res. Commun. 1997 Aug;237(3):663-6
PubMed ID: 9299423