Pseudomonas aeruginosa PAO1, PA0106 (coxA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag
PA0106
Name
coxA
Synonym: coI
Replicon chromosome
Genomic location 128512 - 130104 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 3 transposon mutants in orthologs

Cross-References

RefSeq NP_248796.1
GI 15595304
Affymetrix PA0106_coxA_at
Entrez 881877
GenBank AAG03496.1
INSDC AAG03496.1
NCBI Locus Tag PA0106
protein_id(GenBank) gb|AAG03496.1|AE004449_5|gnl|PseudoCAP|PA0106
TIGR NTL03PA00107
UniParc UPI00000C4F3B
UniProtKB Acc Q9I726
UniProtKB ID Q9I726_PSEAE
UniRef100 UniRef100_W0YJJ2
UniRef50 UniRef50_T2MHZ6
UniRef90 UniRef90_G8PXA8

Product

Feature Type CDS
Coding Frame 1
Product Name
cytochrome c oxidase, subunit I
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 1.00
Kyte-Doolittle Hydrophobicity Value 0.750
Molecular Weight (kDa) 58.8
Isoelectric Point (pI) 7.12

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 2
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 436 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000104 (1031 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0106
Search term: coxA

Human Homologs

Ensembl 94, assembly GRCh38.p12
mitochondrially encoded cytochrome c oxidase I [Source:HGNC Symbol;Acc:HGNC:7419]
E-value: 1.3e-136
Percent Identity: 49.0

References

Cytochrome aa3 gene regulation in members of the family Rhizobiaceae: comparison of copper and oxygen effects in Bradyrhizobium japonicum and Rhizobium tropici.
Gabel C, Bittinger MA, Maier RJ
Appl. Environ. Microbiol. 1994 Jan;60(1):141-8
PubMed ID: 8117073