Pseudomonas aeruginosa PAO1, PA0232 (pcaC)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA0232
Name
pcaC
Replicon chromosome
Genomic location 261981 - 262382 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_248923.1
GI 15595429
Affymetrix PA0232_pcaC_at
DNASU PaCD00006104
Entrez 882116
GenBank AAG03621.1
INSDC AAG03621.1
NCBI Locus Tag PA0232
protein_id(GenBank) gb|AAG03621.1|AE004461_4|gnl|PseudoCAP|PA0232
TIGR NTL03PA00233
UniParc UPI00000C4FAF
UniProtKB Acc Q9I6Q6
UniProtKB ID Q9I6Q6_PSEAE
UniRef100 UniRef100_Q9I6Q6
UniRef50 UniRef50_P20370
UniRef90 UniRef90_A6UY29

Product

Feature Type CDS
Coding Frame 1
Product Name
gamma-carboxymuconolactone decarboxylase
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) 0.16
Kyte-Doolittle Hydrophobicity Value -0.411
Molecular Weight (kDa) 15.1
Isoelectric Point (pI) 7.07

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 247 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000231 (995 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0232
Search term: pcaC

Human Homologs

References

Relationships among enzymes of the beta-ketoadipate pathway. 3. Properties of crystalline gamma-carboxymuconolactone decarboxylase from Pseudomonas putida.
Parke D, Meagher RB, Ornston LN
Biochemistry 1973 Aug 28;12(18):3537-42
PubMed ID: 4199896
Cloning and genetic organization of the pca gene cluster from Acinetobacter calcoaceticus.
Doten RC, Ngai KL, Mitchell DJ, Ornston LN
J Bacteriol 1987 Jul;169(7):3168-74
PubMed ID: 3036773