Pseudomonas aeruginosa PAO1, PA0235 (pcaK)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag
PA0235
Name
pcaK
Replicon chromosome
Genomic location 264964 - 266310 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 6 transposon mutants in orthologs

Cross-References

RefSeq NP_248926.1
GI 15595432
Affymetrix PA0235_pcaK_at
Entrez 881907
GenBank AAG03624.1
INSDC AAG03624.1
NCBI Locus Tag PA0235
protein_id(GenBank) gb|AAG03624.1|AE004461_7|gnl|PseudoCAP|PA0235
TIGR NTL03PA00236
UniParc UPI00000C4FB2
UniProtKB Acc Q9I6Q3
UniProtKB ID PCAK_PSEAE
UniRef100 UniRef100_Q9I6Q3
UniRef50 UniRef50_Q9I6Q3
UniRef90 UniRef90_Q9I6Q3

Product

Feature Type CDS
Coding Frame 1
Product Name
4-hydroxybenzoate transporter PcaK
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) 7.79
Kyte-Doolittle Hydrophobicity Value 0.825
Molecular Weight (kDa) 47.6
Isoelectric Point (pI) 9.37

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 463 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000234 (2463 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0235
Search term: pcaK

Human Homologs

Ensembl 94, assembly GRCh38.p12
SV2 related protein [Source:HGNC Symbol;Acc:HGNC:25417]
E-value: 1.4e-22
Percent Identity: 26.1

References

Identification of the pcaRKF gene cluster from Pseudomonas putida: involvement in chemotaxis, biodegradation, and transport of 4-hydroxybenzoate.
Harwood CS, Nichols NN, Kim MK, Ditty JL, Parales RE
J. Bacteriol. 1994 Nov;176(21):6479-88
PubMed ID: 7961399