Pseudomonas aeruginosa PAO1, PA0280 (cysA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag
PA0280
Name
cysA
Replicon chromosome
Genomic location 313938 - 314927 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_248971.1
GI 15595477
Affymetrix PA0280_cysA_at
Entrez 877644
GenBank AAG03669.1
INSDC AAG03669.1
NCBI Locus Tag PA0280
protein_id(GenBank) gb|AAG03669.1|AE004466_3|gnl|PseudoCAP|PA0280
TIGR NTL03PA00281
UniParc UPI00000C4FDC
UniProtKB Acc Q9I6L0
UniProtKB ID CYSA_PSEAE
UniRef100 UniRef100_Q9I6L0
UniRef50 UniRef50_P16676
UniRef90 UniRef90_Q9I6L0

Product

Feature Type CDS
Coding Frame 1
Product Name
sulfate transport protein CysA
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -6.13
Kyte-Doolittle Hydrophobicity Value -0.217
Molecular Weight (kDa) 36.8
Isoelectric Point (pI) 6.10

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 2
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 669 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000277 (545 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0280
Search term: cysA

Human Homologs

Ensembl 94, assembly GRCh38.p12
ATP binding cassette subfamily B member 4 [Source:HGNC Symbol;Acc:HGNC:45]
E-value: 8.5e-25
Percent Identity: 36.6

References

Sulfate and thiosulfate transport in Escherichia coli K-12: nucleotide sequence and expression of the cysTWAM gene cluster.
Sirko A, Hryniewicz M, Hulanicka D, Böck A
J. Bacteriol. 1990 Jun;172(6):3351-7
PubMed ID: 2188958