Pseudomonas aeruginosa PAO1, PA0341 (lgt)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag
PA0341
Name
lgt
Synonym: umpA
Replicon chromosome
Genomic location 383727 - 384527 (+ strand)
Transposon Mutants 1 transposon mutants in PAO1

Cross-References

RefSeq NP_249032.1
GI 15595538
Affymetrix PA0341_lgt_at
DNASU PaCD00006151
Entrez 882221
GenBank AAG03730.1
INSDC AAG03730.1
NCBI Locus Tag PA0341
protein_id(GenBank) gb|AAG03730.1|AE004472_2|gnl|PseudoCAP|PA0341
TIGR NTL03PA00342
UniParc UPI00000C5016
UniProtKB Acc Q9I6F2
UniProtKB ID LGT_PSEAE
UniRef100 UniRef100_B7V2Q4
UniRef50 UniRef50_Q1H4H7
UniRef90 UniRef90_A6UYE4

Product

Feature Type CDS
Coding Frame 1
Product Name
prolipoprotein diacylglyceryl transferase
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 9.85
Kyte-Doolittle Hydrophobicity Value 0.526
Molecular Weight (kDa) 29.8
Isoelectric Point (pI) 9.93

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Cytoplasmic Membrane Class 2
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 575 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000333 (553 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0341
Search term: lgt

References

The umpA gene of Escherichia coli encodes phosphatidylglycerol:prolipoprotein diacylglyceryl transferase (lgt) and regulates thymidylate synthase levels through translational coupling.
Gan K, Sankaran K, Williams MG, Aldea M, Rudd KE, Kushner SR, Wu HC
J. Bacteriol. 1995 Apr;177(7):1879-82
PubMed ID: 7896715
Structure-function relationship of bacterial prolipoprotein diacylglyceryl transferase: functionally significant conserved regions.
Qi HY, Sankaran K, Gan K, Wu HC
J. Bacteriol. 1995 Dec;177(23):6820-4
PubMed ID: 7592473