Pseudomonas aeruginosa PAO1, PA0413 (chpA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag
PA0413
Name
chpA
Synonym: pilL
Replicon chromosome
Genomic location 454126 - 461544 (+ strand)
Transposon Mutants 4 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_249104.1
GI 15595610
Affymetrix PA0413_at
Entrez 878176
GenBank AAG03802.1
INSDC AAG03802.1
NCBI Locus Tag PA0413
protein_id(GenBank) gb|AAG03802.1|AE004478_7|gnl|PseudoCAP|PA0413
TIGR NTL03PA00414
UniParc UPI00000C5045
UniProtKB Acc Q9I696
UniProtKB ID Q9I696_PSEAE
UniRef100 UniRef100_Q9I696
UniRef50 UniRef50_Q9I696
UniRef90 UniRef90_Q9I696

Product

Feature Type CDS
Coding Frame 1
Product Name
component of chemotactic signal transduction system
Product Name Confidence: Class 1
Synonyms ChpA
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -223.28
Kyte-Doolittle Hydrophobicity Value -0.225
Molecular Weight (kDa) 268.6
Isoelectric Point (pI) 4.15

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Cytoplasmic Class 2
Additional evidence for subcellular localization

Virulence Evidence

Source 1
Database VFDB : VF0082
Category Type IV pili twitching motility related proteins
Evidence
Host Organism
Notes
Reference 9224879

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 623 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000404 (546 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0413
Search term: chpA

References

The molecular genetics of type-4 fimbriae in Pseudomonas aeruginosa--a review.
Mattick JS, Whitchurch CB, Alm RA
Gene 1996 Nov;179(1):147-55
PubMed ID: 8955641
Effect of site-specific mutations in different phosphotransfer domains of the chemosensory protein ChpA on Pseudomonas aeruginosa motility.
Leech AJ, Mattick JS
J. Bacteriol. 2006 Dec;188(24):8479-86
PubMed ID: 17012390