Pseudomonas aeruginosa PAO1, PA0584 (cca)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag
PA0584
Name
cca
Replicon chromosome
Genomic location 641932 - 643164 (- strand)
Transposon Mutants 1 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_249275.1
GI 15595781
Affymetrix PA0584_cca_at
Entrez 877618
GenBank AAG03973.1
INSDC AAG03973.1
NCBI Locus Tag PA0584
protein_id(GenBank) gb|AAG03973.1|AE004494_9|gnl|PseudoCAP|PA0584
TIGR NTL03PA00585
UniParc UPI00000D429C
UniProtKB Acc Q9I5V3
UniProtKB ID CCA_PSEAE
UniRef100 UniRef100_Q9I5V3
UniRef50 UniRef50_Q4K4W8
UniRef90 UniRef90_Q9I5V3

Product

Feature Type CDS
Coding Frame 1
Product Name
tRNA nucleotidyl transferase
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -0.73
Kyte-Doolittle Hydrophobicity Value -0.294
Molecular Weight (kDa) 45.6
Isoelectric Point (pI) 6.89

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

Virulence Evidence

Source 1
Database Victors : 4201
Category Not available / Not known
Evidence ECO:0000315
mutant phenotype evidence used in manual assertion
Host Organism Rattus norvegicus
Notes
Infection model Rat agar bead model of chronic lung infection
Reference 14641575

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 576 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000567 (553 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0584
Search term: cca

References

Cloning, sequencing, and species relatedness of the Escherichia coli cca gene encoding the enzyme tRNA nucleotidyltransferase.
Cudny H, Lupski JR, Godson GN, Deutscher MP
J. Biol. Chem. 1986 May;261(14):6444-9
PubMed ID: 3009457
A mutation in Escherichia coli tRNA nucleotidyltransferase that affects only AMP incorporation is in a sequence often associated with nucleotide-binding proteins.
Zhu LQ, Cudny H, Deutscher MP
J. Biol. Chem. 1986 Nov;261(32):14875-7
PubMed ID: 3533927