Pseudomonas aeruginosa PAO1, PA0592 (ksgA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag
PA0592
Name
ksgA
Replicon chromosome
Genomic location 650575 - 651381 (- strand)
Transposon Mutants 3 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_249283.1
GI 15595789
Affymetrix PA0592_ksgA_at
DNASU PaCD00006261
Entrez 880847
GenBank AAG03981.1
INSDC AAG03981.1
NCBI Locus Tag PA0592
protein_id(GenBank) gb|AAG03981.1|AE004495_5|gnl|PseudoCAP|PA0592
TIGR NTL03PA00593
UniParc UPI000012E0B6
UniProtKB Acc Q9I5U5
UniProtKB ID RSMA_PSEAE
UniRef100 UniRef100_Q9I5U5
UniRef50 UniRef50_Q48NT7
UniRef90 UniRef90_Q9I5U5

Product

Feature Type CDS
Coding Frame 1
Product Name
rRNA (adenine-N6,N6)-dimethyltransferase
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 1.62
Kyte-Doolittle Hydrophobicity Value -0.206
Molecular Weight (kDa) 30.1
Isoelectric Point (pI) 7.44

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 663 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000575 (553 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0592
Search term: ksgA

Human Homologs

Ensembl 94, assembly GRCh38.p12
DIM1 dimethyladenosine transferase 1 homolog [Source:HGNC Symbol;Acc:HGNC:30217]
E-value: 1.4e-25
Percent Identity: 35.9

References

Nucleotide sequence of the ksgA gene of Escherichia coli: comparison of methyltransferases effecting dimethylation of adenosine in ribosomal RNA.
van Buul CP, van Knippenberg PH
Gene 1985 ;38(1-3):65-72
PubMed ID: 3905517