Pseudomonas aeruginosa PAO1, PA0654 (speD)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag
PA0654
Name
speD
Replicon chromosome
Genomic location 707686 - 708480 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_249345.1
GI 15595851
Affymetrix PA0654_speD_at
Entrez 878446
GenBank AAG04043.1
INSDC AAG04043.1
NCBI Locus Tag PA0654
protein_id(GenBank) gb|AAG04043.1|AE004500_9|gnl|PseudoCAP|PA0654
TIGR NTL03PA00655
UniParc UPI0000135DE2
UniProtKB Acc Q9I5R7
UniProtKB ID SPED_PSEAE
UniRef100 UniRef100_B7V612
UniRef50 UniRef50_Q607L0
UniRef90 UniRef90_B7V612

Product

Feature Type CDS
Coding Frame 1
Product Name
S-adenosylmethionine decarboxylase proenzyme
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -18.65
Kyte-Doolittle Hydrophobicity Value -0.382
Molecular Weight (kDa) 30.4
Isoelectric Point (pI) 4.48

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Cytoplasmic Class 1
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 78 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000633 (399 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0654
Search term: speD

References

Escherichia coli S-adenosylmethionine decarboxylase. Subunit structure, reductive amination, and NH2-terminal sequences.
Anton DL, Kutny R
J. Biol. Chem. 1987 Feb;262(6):2817-22
PubMed ID: 3546296
The speEspeD operon of Escherichia coli. Formation and processing of a proenzyme form of S-adenosylmethionine decarboxylase.
Tabor CW, Tabor H
J. Biol. Chem. 1987 Nov;262(33):16037-40
PubMed ID: 3316212