Pseudomonas aeruginosa PAO1, PA0656

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA0656
Name
Synonym: ycfF
Replicon chromosome
Genomic location 709282 - 709620 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_249347.1
GI 15595853
Affymetrix PA0656_at
DNASU PaCD00006296
Entrez 881980
GenBank AAG04045.1
INSDC AAG04045.1
NCBI Locus Tag PA0656
protein_id(GenBank) gb|AAG04045.1|AE004500_11|gnl|PseudoCAP|PA0656
TIGR NTL03PA00657
UniParc UPI00000C50E6
UniProtKB Acc Q9I5R5
UniProtKB ID Q9I5R5_PSEAE
UniRef100 UniRef100_W0YK88
UniRef50 UniRef50_A0A098GCC3
UniRef90 UniRef90_A6UZF7

Product

Feature Type CDS
Coding Frame 1
Product Name
probable HIT family protein
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -1.73
Kyte-Doolittle Hydrophobicity Value -0.193
Molecular Weight (kDa) 12.7
Isoelectric Point (pI) 6.67

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Cytoplasmic Class 1
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 638 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000635 (884 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0656

Human Homologs

Ensembl 110, assembly GRCh38.p14
histidine triad nucleotide binding protein 1 [Source:HGNC Symbol;Acc:HGNC:4912]
E-value: 7.1e-31
Percent Identity: 49.5

References

Structure-based analysis of catalysis and substrate definition in the HIT protein family.
Lima CD, Klein MG, Hendrickson WA
Science 1997 Oct 10;278(5336):286-90
PubMed ID: 9323207