Pseudomonas aeruginosa PAO1, PA0674 (vreA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag
PA0674
Name
vreA
Synonym: pigC
Replicon chromosome
Genomic location 734159 - 734875 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1

Cross-References

RefSeq NP_249365.1
GI 15595871
Affymetrix PA0674_at
DNASU PaCD00006306
Entrez 879213
GenBank AAG04063.1
INSDC AAG04063.1
NCBI Locus Tag PA0674
protein_id(GenBank) gb|AAG04063.1|AE004503_1|gnl|PseudoCAP|PA0674
TIGR NTL03PA00675
UniParc UPI00000D4261
UniProtKB Acc G3XD45
UniProtKB ID G3XD45_PSEAE
UniRef100 UniRef100_W0Z1K6
UniRef50 UniRef50_W0Z1K6
UniRef90 UniRef90_W0Z1K6

Product

Feature Type CDS
Coding Frame 1
Product Name
VreA
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Charge (pH 7) 10.38
Kyte-Doolittle Hydrophobicity Value 0.058
Molecular Weight (kDa) 25.0
Isoelectric Point (pI) 10.85

Subcellular localization

Individual Mappings
Localization Confidence PMID
Periplasmic Class 2
Periplasmic Class 3
Outer Membrane Class 2
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 49 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000653 (369 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0674
Search term: vreA
Search term: VreA

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res. 2005 Feb;15(2):321-9
PubMed ID: 15687295
Gene repression by the ferric uptake regulator in Pseudomonas aeruginosa: cycle selection of iron-regulated genes.
Ochsner UA, Vasil ML
Proc. Natl. Acad. Sci. U.S.A. 1996 Apr;93(9):4409-14
PubMed ID: 8633080
A Novel extracytoplasmic function (ECF) sigma factor regulates virulence in Pseudomonas aeruginosa.
Llamas MA, van der Sar A, Chu BC, Sparrius M, Vogel HJ, Bitter W
PLoS Pathog. 2009 Sep;5(9):e1000572
PubMed ID: 19730690