Pseudomonas aeruginosa PAO1, PA0679 (hxcP)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag
PA0679
Name
hxcP
Replicon chromosome
Genomic location 737677 - 738108 (+ strand)
Transposon Mutants 3 transposon mutants in PAO1
CommentHxc proteins are involved in the secretion of alkaline phosphatase. hxc gene cluster is under phosphate regulation. May belong to the GspC family (general secretory pathway protein C).

Cross-References

RefSeq NP_249370.1
GI 15595876
Affymetrix PA0679_at
DNASU PaCD00006310
Entrez 879201
GenBank AAG04068.1
INSDC AAG04068.1
NCBI Locus Tag PA0679
protein_id(GenBank) gb|AAG04068.1|AE004503_6|gnl|PseudoCAP|PA0679
TIGR NTL03PA00680
UniParc UPI00000C50F8
UniProtKB Acc Q9I5P6
UniProtKB ID Q9I5P6_PSEAE
UniRef100 UniRef100_W0Z1L0
UniRef50 UniRef50_Q02HH1
UniRef90 UniRef90_Q02HH1

Product

Feature Type CDS
Coding Frame 1
Product Name
HxcP
Product Name Confidence: Class 1
Synonyms hypothetical protein
Evidence for Translation
Charge (pH 7) -1.01
Kyte-Doolittle Hydrophobicity Value 0.280
Molecular Weight (kDa) 15.0
Isoelectric Point (pI) 5.16

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 5 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000658 (325 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0679
Search term: hxcP
Search term: HxcP

References

A novel type II secretion system in Pseudomonas aeruginosa.
Ball G, Durand E, Lazdunski A, Filloux A
Mol. Microbiol. 2002 Jan;43(2):475-85
PubMed ID: 11985723
Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res. 2005 Feb;15(2):321-9
PubMed ID: 15687295