Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA0710
|
Name |
gloA2
|
Replicon | chromosome |
Genomic location | 782570 - 782965 (+ strand) |
Transposon Mutants | 3 transposon mutants in PAO1 |
RefSeq | NP_249401.1 |
GI | 15595907 |
Affymetrix | PA0710_gloA2_at |
DNASU | PaCD00006326 |
Entrez | 878796 |
GenBank | AAG04099.1 |
INSDC | AAG04099.1 |
NCBI Locus Tag | PA0710 |
protein_id(GenBank) | gb|AAG04099.1|AE004506_9|gnl|PseudoCAP|PA0710 |
TIGR | NTL03PA00711 |
UniParc | UPI00000C5113 |
UniProtKB Acc | Q9I5L8 |
UniProtKB ID | Q9I5L8_PSEAE |
UniRef100 | UniRef100_Q9I5L8 |
UniRef50 | UniRef50_W6M5E2 |
UniRef90 | UniRef90_Q9I5L8 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
lactoylglutathione lyase
|
Synonyms |
glyoxalase I |
Evidence for Translation | |
Charge (pH 7) | -3.08 |
Kyte-Doolittle Hydrophobicity Value | -0.363 |
Molecular Weight (kDa) | 14.9 |
Isoelectric Point (pI) | 5.64 |
Individual Mappings | |
Additional evidence for subcellular localization |
Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
4MTQ | LYASE | 09/20/13 | Ni-bound GloA2 | Pseudomonas aeruginosa | 2.17 | X-RAY DIFFRACTION | 100.0 |
4MTT | LYASE | 09/20/13 | Ni- and Zn-bound GloA2 at low resolution | Pseudomonas aeruginosa | 2.17 | X-RAY DIFFRACTION | 100.0 |
4MTR | LYASE | 09/20/13 | Zn-bound GloA2 | Pseudomonas aeruginosa | 1.83 | X-RAY DIFFRACTION | 100.0 |
4MTS | LYASE | 09/20/13 | Ni- and Zn-bound GloA2 at high resolution | Pseudomonas aeruginosa | 1.8 | X-RAY DIFFRACTION | 100.0 |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 324 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG000687 (301 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA0710
Search term: gloA2
Search term: lactoylglutathione lyase
|
Isolation and sequencing of a gene coding for glyoxalase I activity from Salmonella typhimurium and comparison with other glyoxalase I sequences.
Clugston SL, Daub E, Kinach R, Miedema D, Barnard JF, Honek JF
Gene 1997 Feb 20;186(1):103-11
PubMed ID: 9047352
|
Pseudomonas aeruginosa contains multiple glyoxalase I-encoding genes from both metal activation classes.
Sukdeo N, Honek JF
Biochim Biophys Acta 2007 Jun;1774(6):756-63
PubMed ID: 17513180
|