Pseudomonas aeruginosa PAO1, PA0757

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag
PA0757
Name
Replicon chromosome
Genomic location 825073 - 826455 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_249448.1
GI 15595954
Affymetrix PA0757_at
Entrez 880811
GenBank AAG04146.1
INSDC AAG04146.1
NCBI Locus Tag PA0757
protein_id(GenBank) gb|AAG04146.1|AE004510_10|gnl|PseudoCAP|PA0757
TIGR NTL03PA00758
UniParc UPI00000C513F
UniProtKB Acc Q9I5H2
UniProtKB ID Q9I5H2_PSEAE
UniRef100 UniRef100_Q9I5H2
UniRef50 UniRef50_Q4KGR3
UniRef90 UniRef90_Q9I5H2

Product

Feature Type CDS
Coding Frame 1
Product Name
probable two-component sensor
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Charge (pH 7) -12.08
Kyte-Doolittle Hydrophobicity Value -0.017
Molecular Weight (kDa) 50.3
Isoelectric Point (pI) 4.98

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 618 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000731 (546 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0757

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res. 2005 Feb;15(2):321-9
PubMed ID: 15687295
Genetic regulation of the tricarboxylate transport operon (tctI) of Salmonella typhimurium.
Widenhorn KA, Somers JM, Kay WW
J. Bacteriol. 1989 Aug;171(8):4436-41
PubMed ID: 2666399
Identification and characterization of a two-component regulatory system involved in invasion of eukaryotic cells and heavy-metal resistance in Burkholderia pseudomallei.
Jones AL, DeShazer D, Woods DE
Infect. Immun. 1997 Dec;65(12):4972-7
PubMed ID: 9393784