Pseudomonas aeruginosa PAO1, PA0795 (prpC)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag
PA0795
Name
prpC
Replicon chromosome
Genomic location 872986 - 874113 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_249486.1
GI 15595992
Affymetrix PA0795_prpC_at
Entrez 880674
GenBank AAG04184.1
INSDC AAG04184.1
NCBI Locus Tag PA0795
protein_id(GenBank) gb|AAG04184.1|AE004514_7|gnl|PseudoCAP|PA0795
TIGR NTL03PA00796
UniParc UPI00000C5158
UniProtKB Acc Q9I5E3
UniProtKB ID Q9I5E3_PSEAE
UniRef100 UniRef100_W0YL54
UniRef50 UniRef50_Q56063
UniRef90 UniRef90_A6VAI0

Product

Feature Type CDS
Coding Frame 1
Product Name
citrate synthase 2
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -3.47
Kyte-Doolittle Hydrophobicity Value -0.234
Molecular Weight (kDa) 41.7
Isoelectric Point (pI) 6.44

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 550 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000768 (553 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0795
Search term: prpC

References

Does Escherichia coli possess a second citrate synthase gene?
Patton AJ, Hough DW, Towner P, Danson MJ
Eur. J. Biochem. 1993 May;214(1):75-81
PubMed ID: 8508809
Propionate catabolism in Salmonella typhimurium LT2: two divergently transcribed units comprise the prp locus at 8.5 centisomes, prpR encodes a member of the sigma-54 family of activators, and the prpBCDE genes constitute an operon.
Horswill AR, Escalante-Semerena JC
J. Bacteriol. 1997 Feb;179(3):928-40
PubMed ID: 9006051