Pseudomonas aeruginosa PAO1, PA0871 (phhB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag
PA0871
Name
phhB
Replicon chromosome
Genomic location 952158 - 952514 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_249562.1
GI 15596068
Affymetrix PA0871_phhB_at
Entrez 880827
GenBank AAG04260.1
INSDC AAG04260.1
NCBI Locus Tag PA0871
protein_id(GenBank) gb|AAG04260.1|AE004522_2|gnl|PseudoCAP|PA0871
TIGR NTL03PA00872
UniParc UPI0000131A2D
UniProtKB Acc P43335
UniProtKB ID PHS_PSEAE
UniRef100 UniRef100_P43335
UniRef50 UniRef50_P43335
UniRef90 UniRef90_P43335

Product

Feature Type CDS
Coding Frame 1
Product Name
pterin-4-alpha-carbinolamine dehydratase
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -2.39
Kyte-Doolittle Hydrophobicity Value -0.336
Molecular Weight (kDa) 13.3
Isoelectric Point (pI) 6.39

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 217 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000838 (549 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0871
Search term: phhB

References

Pseudomonas aeruginosa possesses homologues of mammalian phenylalanine hydroxylase and 4 alpha-carbinolamine dehydratase/DCoH as part of a three-component gene cluster.
Zhao G, Xia T, Song J, Jensen RA
Proc. Natl. Acad. Sci. U.S.A. 1994 Feb;91(4):1366-70
PubMed ID: 8108417