Pseudomonas aeruginosa PAO1, PA0966 (ruvA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag
PA0966
Name
ruvA
Replicon chromosome
Genomic location 1051673 - 1052278 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_249657.1
GI 15596163
Affymetrix PA0966_ruvA_at
DNASU PaCD00006443
Entrez 879609
GenBank AAG04355.1
INSDC AAG04355.1
NCBI Locus Tag PA0966
protein_id(GenBank) gb|AAG04355.1|AE004530_8|gnl|PseudoCAP|PA0966
TIGR NTL03PA00967
UniParc UPI0000135357
UniProtKB Acc Q51425
UniProtKB ID RUVA_PSEAE
UniRef100 UniRef100_A6VA06
UniRef50 UniRef50_A6VA06
UniRef90 UniRef90_A6VA06

Product

Feature Type CDS
Coding Frame 1
Product Name
Holliday junction DNA helicase RuvA
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -2.07
Kyte-Doolittle Hydrophobicity Value 0.037
Molecular Weight (kDa) 21.9
Isoelectric Point (pI) 6.14

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 580 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000931 (552 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0966
Search term: ruvA

References

Crystal structure of DNA recombination protein RuvA and a model for its binding to the Holliday junction.
Rafferty JB, Sedelnikova SE, Hargreaves D, Artymiuk PJ, Baker PJ, Sharples GJ, Mahdi AA, Lloyd RG, Rice DW
Science 1996 Oct;274(5286):415-21
PubMed ID: 8832889
Molecular analysis of the Pseudomonas aeruginosa genes, ruvA, ruvB and ruvC, involved in processing of homologous recombination intermediates.
Hishida T, Iwasaki H, Ishioka K, Shinagawa H
Gene 1996 Dec;182(1-2):63-70
PubMed ID: 8982068