Pseudomonas aeruginosa PAO1, PA0970 (tolR)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag
PA0970
Name
tolR
Replicon chromosome
Genomic location 1054566 - 1055006 (+ strand)

Cross-References

RefSeq NP_249661.1
GI 15596167
Affymetrix PA0970_tolR_at
DNASU PaCD00006445
Entrez 882113
GenBank AAG04359.1
INSDC AAG04359.1
NCBI Locus Tag PA0970
protein_id(GenBank) gb|AAG04359.1|AE004530_12|gnl|PseudoCAP|PA0970
TIGR NTL03PA00971
UniParc UPI0000137116
UniProtKB Acc P50599
UniProtKB ID TOLR_PSEAE
UniRef100 UniRef100_P50599
UniRef50 UniRef50_P50599
UniRef90 UniRef90_P50599

Product

Feature Type CDS
Coding Frame 1
Product Name
TolR protein
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -0.77
Kyte-Doolittle Hydrophobicity Value 0.045
Molecular Weight (kDa) 15.8
Isoelectric Point (pI) 5.88

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Cytoplasmic Membrane Class 1
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 312 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000935 (553 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0970
Search term: tolR
Search term: TolR protein

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res. 2005 Feb;15(2):321-9
PubMed ID: 15687295
Effects of iron and temperature on expression of the Pseudomonas aeruginosa tolQRA genes: role of the ferric uptake regulator.
Lafontaine ER, Sokol PA
J. Bacteriol. 1998 Jun;180(11):2836-41
PubMed ID: 9603869